SCHEMBL25628804

SCHEMBL25628804

CS(=O)(=O)c1c(F)cc([SH](c2ccccc2)c2ccccc2)cc1F

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.33
PTGS2 P35354 6/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CASP1 P29466 1/20 0.32
KDM4E B2RXH2 3/20 0.32
GAA P10253 3/20 0.32
ALDH1A1 P00352 3/20 0.32
GLA P06280 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KEAP1 Q14145 1/20 0.31
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25628839 1.00 ACLY (0.33) ACLYPTGS2HPGDMEN1KMT2A
SCHEMBL25628840 0.83 PSIP1 (0.41) MEN1KMT2AL3MBTL1
SCHEMBL25628838 0.83 PSIP1 (0.41) MEN1KMT2AL3MBTL1
SCHEMBL25628842 0.81 PTGS1 (0.36) PTGS2L3MBTL1
SCHEMBL25628802 0.79 CCR2 (0.37) ACLYPTGS2L3MBTL1
SCHEMBL25628801 0.78 MEN1 (0.36) PTGS2HPGDMEN1KMT2AKDM4E
SCHEMBL25630083 0.74 ACHE (0.33)
SCHEMBL26836440 0.74 ACHE (0.33)
SCHEMBL25630199 0.71 PTGS2 (0.53) PTGS2
SCHEMBL25630094 0.70 ACHE (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667605-B2 Resist composition, method of forming resist pattern, compound, acid generator, and method of producing compound TOKYO OHKA KOGYO CO., LTD. (JP) 2023-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667605-B2 Resist composition, method of forming resist pattern, compound, acid generator, and method of producing compound RB1, RBBP5, RRM2B ACLY 722/4885PTGS2 3802/4885HPGD 3058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.