SCHEMBL25628802

SCHEMBL25628802

CS(=O)(=O)c1ccc([SH](c2ccccc2)c2ccccc2)cc1F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 3/20 0.37
ACLY P53396 1/20 0.37
GRM4 Q14833 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
PTGS2 P35354 2/20 0.31
BCAT2 O15382 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25628770 0.80 ABCB11 (0.38) CCR2PIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL25628839 0.79 ACLY (0.33) ACLYL3MBTL1PTGS2
SCHEMBL25628804 0.79 ACLY (0.33) ACLYL3MBTL1PTGS2
SCHEMBL26821735 0.74 RAB9A (0.35)
SCHEMBL25696883 0.74 RAB9A (0.35)
SCHEMBL25630199 0.72 PTGS2 (0.53) PTGS2
SCHEMBL644662 0.70 CCR2 (0.57) CCR2L3MBTL1PTGS2
SCHEMBL30784479 0.70 CCR2 (0.57) CCR2L3MBTL1PTGS2
SCHEMBL25628943 0.70 PTGS2 (0.46) PTGS2
SCHEMBL514170 0.69 ALDH1A1 (0.44) ACLYL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667605-B2 Resist composition, method of forming resist pattern, compound, acid generator, and method of producing compound TOKYO OHKA KOGYO CO., LTD. (JP) 2023-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667605-B2 Resist composition, method of forming resist pattern, compound, acid generator, and method of producing compound RB1, RBBP5, RRM2B CCR2 3825/4885ACLY 722/4885GRM4 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.