SCHEMBL25698684

SCHEMBL25698684

COCc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDK2 Q15119 1/20 0.41
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA2 P00918 2/20 0.37
FFAR1 O14842 1/20 0.35
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA7 P43166 3/20 0.35
CA4 P22748 2/20 0.34
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19072681 0.85 ALOX15 (0.44) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL12552835 0.81 ALOX15 (0.41) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL4958672 0.79 ALDH1A1 (0.60) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL7599687 0.78 ALOX15 (0.50) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL434869 0.78 ALOX15 (0.50) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL7932524 0.78 MAOA (0.50) TDP1PDK2
SCHEMBL2601919 0.78 RAB9A (0.65) LMNATP53ALOX15TDP1PDK2
SCHEMBL3747320 0.77 ALDH1A1 (0.38) LMNAALOX15TDP1ALDH1A1NPC1
SCHEMBL24450208 0.76 GSTP1 (0.56) RAB9AFFAR1GRM5
SCHEMBL19950404 0.76 CNR1 (0.50) LMNAALOX15TDP1PDK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192592-A1 MONOMER AND POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-06-22 US disclosed
US-20230192592-A1 MONOMER AND POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192592-A1 MONOMER AND POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE PYM1, RAD51, CRY1 LMNA 1980/4885TP53 2925/4885ALOX15 2919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.