SCHEMBL2601919

SCHEMBL2601919

COCc1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.65
ALDH1A1 P00352 5/20 0.65
NPC1 O15118 5/20 0.65
SMN1; SMN2 Q16637 5/20 0.65
MAPK1 P28482 4/20 0.65
LMNA P02545 4/20 0.65
MAPT P10636 4/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
ELANE P08246 1/20 0.50
PDK2 Q15119 1/20 0.48
HSP90AB1 P08238 1/20 0.47
TUBB4A P04350 2/20 0.46
TUBB P07437 2/20 0.46
TUBA3C P0DPH7 2/20 0.46
TUBA1B P68363 2/20 0.46
TUBA4A P68366 2/20 0.46
TUBB4B P68371 2/20 0.46
TUBB3 Q13509 2/20 0.46
TUBB2A Q13885 2/20 0.46
TUBB8 Q3ZCM7 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22363964 0.85 RAB9A (0.47) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL15082755 0.82 NPC1 (0.61) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL8849788 0.82 S100A4 (0.52) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL18015979 0.81 NPC1 (0.59) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL21131211 0.80 NPC1 (0.57) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL17762970 0.80 MAPT (0.57) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL8849357 0.79 MAPT (0.41) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL2601920 0.79 NPC1 (0.56) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL4954471 0.79 NPC1 (0.56) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1
SCHEMBL599540 0.79 MAPT (0.56) RAB9AALDH1A1NPC1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265318-A1 DOUBLE-SIDED TISSUE TAPE AND RELATED ARTICLE 3M INNOVATIVE PROPERTIES COMPANY 2023-08-24 US disclosed
US-10754198-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
US-10189771-B2 Acrylic adhesive composition from protected photocrosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-01-29 US disclosed
EP-3259290-B1 ACRYLIC ADHESIVE COMPOSITION FROM PROTECTED PHOTOCROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2018-12-12 EP disclosed
US-10093753-B2 Syrup polymer compositions and adhesives therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-10-09 US disclosed
US-20180113337-A1 LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2018-04-26 US disclosed
US-20180029970-A1 ACRYLIC ADHESIVE COMPOSITION FROM PROTECTED PHOTOCROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2018-02-01 US disclosed
US-20170362348-A1 SYRUP POLYMER COMPOSITIONS AND ADHESIVES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2017-12-21 US disclosed
US-9803114-B2 Acrylic adhesive composition with controlled molecular weight 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-10-31 US disclosed
US-20170146478-A1 ANALYTE SENSOR PARKER INTANGIBLES LLC 2017-05-25 US disclosed
US-8980967-B2 Pressure-sensitive adhesives with mixed photocrosslinking system 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-17 US disclosed
US-8956519-B2 Device for detecting an analyte SENOVA SYSTEMS, INC. (US) 2015-02-17 US disclosed
US-8956519-B2 Device for detecting an analyte SENOVA SYSTEMS, INC. (US) 2015-02-17 US disclosed
US-20150027887-A1 ANALYTE SENSOR PARKER INTANGIBLES LLC 2015-01-29 US disclosed
WO-2013112767-A9 ANALYTE SENSOR SENOVA SYSTEMS, INC. (US) 2014-10-09 WO disclosed
US-20140039083-A1 PRESSURE-SENSITIVE ADHESIVES WITH MIXED PHOTOCROSSLINKING SYSTEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-06 US disclosed
WO-2013112767-A1 ANALYTE SENSOR SENOVA SYSTEMS, INC. (US) 2013-08-01 WO disclosed
US-20130168609-A1 ANALYTE SENSOR SENOVA SYSTEMS, INC. (US) 2013-07-04 US disclosed
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE SENOVA SYSTEMS, INC. (US) 2012-04-19 US disclosed
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE SENOVA SYSTEMS, INC. (US) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180029970-A1 ACRYLIC ADHESIVE COMPOSITION FROM PROTECTED PHOTOCROSSLINKING AGENTS DCLRE1A, RAD51, COL2A1 RAB9A 3718/4885ALDH1A1 316/4885NPC1 4883/4885
US-20170146478-A1 ANALYTE SENSOR HAO2, PRDX1, MPO RAB9A 2464/4885ALDH1A1 516/4885NPC1 4884/4885
US-10189771-B2 Acrylic adhesive composition from protected photocrosslinking agents DCLRE1A, RAD51, COL2A1 RAB9A 3718/4885ALDH1A1 316/4885NPC1 4883/4885
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE GPX4, GPX1, AOX1 RAB9A 3669/4885ALDH1A1 279/4885NPC1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.