Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CATSPER1 | Q8NEC5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182010 | 0.80 | CES2 (0.71) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL24554622 | 0.74 | KDM4E (0.53) | HPGDSLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL6793430 | 0.74 | HPGDS (0.83) | HPGDSCES2CES1LMNAHPGD | |
| Cyclopentane SCHEMBL8081415 | 0.74 | HPGDS (0.63) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL6494787 | 0.72 | HPGD (0.72) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL9148337 | 0.72 | LMNA (0.85) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL7554202 | 0.72 | HPGDS (0.71) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL29463149 | 0.72 | LMNA (0.50) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL13714169 | 0.72 | NPC1 (0.51) | HPGDSCES2CES1LMNAHPGD | |
| SCHEMBL158020 | 0.71 | HPGDS (1.00) | HPGDSCES2CES1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837613-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837613-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9153784-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-9153784-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20150270490-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270490-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-2611851-B1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-20130161567-A1 | CONJUGATED POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-27 | — | — | US | disclosed |
| US-20130161567-A1 | CONJUGATED POLYMERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-27 | — | — | US | disclosed |
| US-8173766-B2 | Polymers derived from bis(thienocyclopenta) benzothiadiazole and their use as organic semiconductors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173766-B2 | Polymers derived from bis(thienocyclopenta) benzothiadiazole and their use as organic semiconductors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | disclosed |
| WO-2012028246-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-20110178236-A1 | POLYMERS DERIVED FROM BIS(THIENOCYCLOPENTA) BENZOTHIADIAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-21 | — | — | US | disclosed |
| US-20110178236-A1 | POLYMERS DERIVED FROM BIS(THIENOCYCLOPENTA) BENZOTHIADIAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-21 | — | — | US | disclosed |
| WO-2010031479-A1 | POLYMERS DERIVED FROM BIS(THIENOCYCLOPENTA)BENZOTHIADIAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150270490-A1 | CONJUGATED POLYMERS | OCIAD2, PARG, PPOX | HPGDS 2247/4885CES2 1023/4885CES1 3069/4885 |
| US-20130161567-A1 | CONJUGATED POLYMERS | OCIAD2, PARG, PPOX | HPGDS 2247/4885CES2 1023/4885CES1 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.