Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 3/20 | 0.35 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760105 | 0.87 | ALOX5 (0.51) | KMT2AALOX5PTGS1PTGS2LMNA | |
| SCHEMBL25760150 | 0.87 | GABRA1 (0.47) | LMNAGAAGABRA1GABRB1CYP1A2 | |
| SCHEMBL10549570 | 0.79 | ALOX5 (0.55) | KMT2AALOX5PTGS1PTGS2LMNA | |
| SCHEMBL10554155 | 0.77 | GLRA3 (0.50) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL25760144 | 0.77 | GABRA1 (0.44) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL20099506 | 0.76 | GABRA1 (0.42) | ALOX5PTGS1PTGS2LMNARECQL | |
| SCHEMBL11699535 | 0.74 | SMN1; SMN2 (0.43) | LMNARECQLGAAGABRA1GABRB1 | |
| SCHEMBL25760457 | 0.74 | LMNA (0.36) | KMT2AALOX5PTGS1PTGS2LMNA | |
| SCHEMBL10549863 | 0.74 | PTGS2 (0.46) | KMT2AALOX5PTGS1PTGS2LMNA | |
| SCHEMBL11611475 | 0.73 | CA12 (0.49) | KMT2ALMNARECQLGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11684590-B2 | Substituted alkylphenols as HCN1 antagonists | CORNELL UNIVERSITY (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11684590-B2 | Substituted alkylphenols as HCN1 antagonists | HCN1, HCN2, HCN3 | KMT2A 3842/4885ALOX5 1288/4885PTGS1 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.