SCHEMBL2582572

SCHEMBL2582572

Cc1cccc(Nc2cccc3ccccc23)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.67
ALDH1A1 P00352 2/20 0.67
TP53 P04637 1/20 0.67
CYP3A4 P08684 1/20 0.67
HPGD P15428 1/20 0.67
ALOX15 P16050 1/20 0.67
TSHR P16473 1/20 0.67
ATM Q13315 1/20 0.67
HSD17B10 Q99714 1/20 0.67
FADS1 O60427 1/20 0.65
NPSR1 Q6W5P4 1/20 0.58
RAB9A P51151 2/20 0.54
NPC1 O15118 1/20 0.53
MAPT P10636 3/20 0.52
KDM4E B2RXH2 2/20 0.52
GAA P10253 2/20 0.52
MEN1 O00255 1/20 0.52
GLA P06280 1/20 0.52
RECQL P46063 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30074722 1.00 CDC25B (0.67) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL11587472 0.87 CDC25B (0.63) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL29458805 0.87 NPSR1 (0.51) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL28226651 0.87 NPSR1 (0.51) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL10338322 0.87 CDC25B (0.80) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL28613252 0.86 NPSR1 (0.55) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL1922073 0.85 NPSR1 (0.72) ALDH1A1CYP3A4HSD17B10NPSR1MAPT
SCHEMBL7527181 0.83 NPSR1 (0.64) CYP3A4NPSR1MAPTTDP1CCR4
SCHEMBL21525100 0.82 CDC25B (0.67) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL30575369 0.81 CDC25B (0.71) CDC25BALDH1A1TP53CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11502261-B2 Compound and organic light emitting device using the same LG CHEM LTD. (KR) 2022-11-15 US disclosed
EP-3564249-B1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-01-20 EP disclosed
EP-3564249-B1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEMICAL LTD (KR) 2021-01-20 EP disclosed
CN-107778309-B Quinoline derivative and application thereof 北京鼎材科技有限公司 2020-10-16 CN disclosed
US-20200058885-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2020-02-20 US disclosed
US-20200058885-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2020-02-20 US disclosed
EP-3564249-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG Chem, Ltd. (KR) 2019-11-06 EP disclosed
EP-3564249-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG Chem, Ltd. (KR) 2019-11-06 EP disclosed
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS LANXESS CORPORATION 2018-03-22 US disclosed
CN-107778309-A A kind of and quinoline and its application 北京鼎材科技有限公司 2018-03-09 CN disclosed
WO-2005090512-A1 NEW MATERIALS FOR INJECTING OR TRANSPORTING HOLES AND ORGANIC ELECTROLUMINESCENCE DEVICES USING THE SAME LG CHEM, LTD. (KR) 2005-09-29 WO disclosed
US-6861162-B2 Doped thin films; multilayer; electrolytic cells; light emitting diodes CITYU RESEARCH LTD. (CN) 2005-03-01 US disclosed
US-6833202-B2 Luminescent layer uses as salicylaldiminato Schiff bases or their metal complexes based on diaminomaleonitrile and salicylaldehyde derivatives as red-emitting materials; color chromaticity CITY UNIVERSITY OF HONG KONG (CN) 2004-12-21 US disclosed
US-20040180234-A1 Electroluminescent devices HONG KONG, CITY UNIVERSITY OF (CN) 2004-09-16 US disclosed
US-20040049080-A1 Novel triphenylamines and use thereof SHIROTA, YASUHIKO (JP) 2004-03-11 US disclosed
US-20040043247-A1 Organic electroluminescence devices using pyrazolo [3,4B] quinoxaline derivatives INTELLECTUAL VENTURES HOLDING 57 LLC 2004-03-04 US disclosed
EP-1300390-A1 NOVEL TRIPHENYLAMINES AND USE THEREOF BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-09 EP disclosed
EP-0167820-B1 PROCESS FOR THE PREPARATION OF OPTIONALLY SUBSTITUTED BENZ(C,D)-INDOL-2-ONES (NAPHTHOLACTAMES) BAYER AG (DE) 1989-04-26 EP disclosed
EP-0167820-A2 Process for the preparation of optionally substituted benz(c,d)-indol-2-ones (naphtholactames) BAYER AG (DE) 1986-01-15 EP disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180234-A1 Electroluminescent devices SLC25A13, AOC1, DDT CDC25B 3157/4885ALDH1A1 37/4885TP53 3162/4885
US-11502261-B2 Compound and organic light emitting device using the same TRPA1, CRY1, TMEM109 CDC25B 2052/4885ALDH1A1 27/4885TP53 3995/4885
US-20040049080-A1 Novel triphenylamines and use thereof NAT1, TPR, PNMT CDC25B 301/4885ALDH1A1 1300/4885TP53 566/4885
US-20200058885-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME TMEM109, CRY1, TRPA1 CDC25B 2077/4885ALDH1A1 28/4885TP53 4544/4885
US-20180079984-A1 ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS GPX4, CAT, SOD1 CDC25B 2735/4885ALDH1A1 50/4885TP53 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.