Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455913 | 0.71 | PRMT5 (0.60) | CRHR1PRMT5 | |
| SCHEMBL18368385 | 0.64 | DPP4 (0.39) | — | |
| SCHEMBL12831721 | 0.62 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL18368377 | 0.61 | KEAP1 (0.46) | — | |
| SCHEMBL12730329 | 0.61 | SMN1; SMN2 (0.37) | CRHR1PRMT5CASR | |
| SCHEMBL12831727 | 0.61 | TSHR (0.42) | CRHR1 | |
| SCHEMBL14931059 | 0.60 | GABRA1 (0.44) | — | |
| SCHEMBL22063132 | 0.60 | LMNA (0.33) | CASR | |
| SCHEMBL3216688 | 0.59 | SMN1; SMN2 (0.46) | CRHR1PRMT5 | |
| SCHEMBL2524323 | 0.59 | CRHR1 (0.37) | CRHR1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | ITGB6, ITGA6, GP6 | CRHR1 4746/4885PRMT5 3274/4885CASR 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.