Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587439 | 0.87 | CTSS (0.41) | MAPTKCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2575528 | 0.86 | ALDH1A1 (0.47) | ERCC5FEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2581151 | 0.83 | CHRNA1 (0.36) | ALDH1A1MAPTSLC6A2CHRNA1CHRNG | |
| SCHEMBL2459388 | 0.80 | PLOD2 (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2585429 | 0.80 | CTSS (0.33) | SLC6A3LMNA | |
| SCHEMBL2584672 | 0.79 | AAK1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL2587766 | 0.76 | CTSS (0.35) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL840032 | 0.76 | EGFR (0.50) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4521097 | 0.76 | CTSL (0.52) | ERCC5FEN1CTSLALDH1A1MAPT | |
| SCHEMBL4521105 | 0.76 | CTSL (0.52) | ERCC5FEN1CTSLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |