Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.37 |
| ▸ | WNT3A | P56704 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585429 | 0.89 | CTSS (0.33) | CTSSCTSKLMNA | |
| SCHEMBL2583802 | 0.87 | ERCC5 (0.42) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2581151 | 0.86 | CHRNA1 (0.36) | NPC1RAB9AMAPTHPGDMEN1 | |
| SCHEMBL2584672 | 0.83 | AAK1 (0.34) | CTSSCTSKRAB9AMAPTHPGD | |
| SCHEMBL2578534 | 0.83 | ACKR3 (0.40) | CTSSCTSKCES2CES1 | |
| SCHEMBL2587766 | 0.83 | CTSS (0.35) | CTSSCTSKKDM4EMAPTHPGD | |
| SCHEMBL2588125 | 0.81 | AAK1 (0.36) | CTSSCTSK | |
| SCHEMBL2459388 | 0.80 | PLOD2 (0.44) | RAB9AMEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL2575528 | 0.80 | ALDH1A1 (0.47) | MAPTHPGDLMNAMEN1TSHR | |
| SCHEMBL2588069 | 0.79 | AAK1 (0.34) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |