SCHEMBL25849141

SCHEMBL25849141

CCCCCc1ccc(-c2cc3ccc(SCC(COC(=O)C(C)C)C(F)(F)F)cc3oc2=O)c(OC(F)(F)F)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 3/20 0.32
KDM4E B2RXH2 3/20 0.31
MEN1 O00255 2/20 0.31
APAF1 O14727 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
KMT2A Q03164 2/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
BLM P54132 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SLC10A1 Q14973 1/20 0.31
STS P08842 1/20 0.31
CNR1 P21554 3/20 0.31
CNR2 P34972 3/20 0.31
GPR18 Q14330 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849289 0.91 GPR55 (0.31) GPR55KDM4EMEN1APAF1POLB
SCHEMBL22624914 0.91 STS (0.30) STS
SCHEMBL25848173 0.85 FPR1 (0.30) STS
SCHEMBL25848233 0.83 PPARD (0.31)
SCHEMBL21735043 0.82 ALOX5 (0.30) ALDH1A1
SCHEMBL21735038 0.82 THRB (0.35)
SCHEMBL25751858 0.80 MAOB (0.47) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL22624953 0.80 TERT (0.33) STS
SCHEMBL22625004 0.80 TERT (0.31)
SCHEMBL22625021 0.80 KDM4E (0.41) GPR55KDM4EMEN1APAF1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702396-B2 Hydrophobic compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702396-B2 Hydrophobic compounds for optically active devices UACA, CRYZ, TRPA1 GPR55 650/4885KDM4E 4579/4885MEN1 3033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.