Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063759 | 0.90 | ACHE (0.48) | MEN1KMT2APTPN1ABCB1ACHE | |
| SCHEMBL25860654 | 0.86 | PDE4D (0.40) | PTPN1PPARDGAAPDE4D | |
| SCHEMBL22063576 | 0.86 | PDE4D (0.48) | ALDH1A1ACHEPDE4DSMN1; SMN2 | |
| SCHEMBL25860652 | 0.80 | SLC6A3 (0.38) | LMNAMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL22063573 | 0.78 | BACE1 (0.44) | ALDH1A1USP2LMNAMEN1KMT2A | |
| SCHEMBL22063647 | 0.69 | NFE2L2 (0.44) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL3301366 | 0.65 | CYP1A2 (0.46) | ALDH1A1KMT2AGAA | |
| SCHEMBL22063648 | 0.65 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAMEN1KMT2A | |
| SCHEMBL3112694 | 0.65 | ALDH1A1 (0.35) | ALDH1A1KMT2APTPN1 | |
| SCHEMBL22063652 | 0.64 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | DUOX1, DUOX2, ALDH3A1 | ALDH1A1 149/4885POLB 487/4885USP2 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.