Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.40 |
| ▸ | MMP9 | P14780 | 11/20 | 0.40 |
| ▸ | MMP3 | P08254 | 11/20 | 0.40 |
| ▸ | MMP1 | P03956 | 11/20 | 0.40 |
| ▸ | MMP2 | P08253 | 11/20 | 0.40 |
| ▸ | MMP7 | P09237 | 9/20 | 0.40 |
| ▸ | MMP8 | P22894 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25880760 | 0.89 | MMP13 (0.37) | MMP13MMP9MMP3MMP1MMP2 | |
| SCHEMBL25880720 | 0.88 | MMP13 (0.38) | MMP13MMP9MMP3MMP1MMP2 | |
| SCHEMBL25877328 | 0.86 | MMP7 (0.42) | MMP13MMP9MMP3MMP1MMP2 | |
| SCHEMBL25877986 | 0.83 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL25878425 | 0.83 | CTSV (0.31) | — | |
| SCHEMBL25878269 | 0.81 | HCRTR1 (0.30) | — | |
| SCHEMBL25880702 | 0.81 | ADAM17 (0.40) | SLC1A3SLC1A2SLC1A1ADAM17 | |
| SCHEMBL25877760 | 0.81 | HSD11B1 (0.36) | MMP13MMP9MMP3MMP1MMP2 | |
| SCHEMBL25664730 | 0.79 | CTSV (0.33) | — | |
| SCHEMBL25878684 | 0.78 | NR3C1 (0.35) | MMP13MMP9MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234921-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | ASCLETIS BIOSCIENCE CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234921-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | SERPINB1, CTSV, CTSE | MMP13 130/4885MMP9 179/4885MMP3 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.