SCHEMBL25895759

SCHEMBL25895759

COc1cccc2c1N=CCC2

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 1/20 0.41
DRD2 P14416 4/20 0.38
DRD3 P35462 4/20 0.38
CHRM2 P08172 3/20 0.37
CHRM1 P11229 3/20 0.37
CHRM3 P20309 3/20 0.37
DRD1 P21728 1/20 0.37
DRD5 P21918 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
DRD4 P21917 2/20 0.36
PTGS2 P35354 1/20 0.36
PNMT P11086 1/20 0.36
ADRA2A P08913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31061252 1.00 HTR5A (0.41) HTR5ADRD2DRD3CHRM2CHRM1
SCHEMBL28227231 0.82 DRD2 (0.36) DRD2DRD3DRD1DRD4
SCHEMBL21255695 0.81 HTR5A (0.42) HTR5ADRD2DRD3CHRM2CHRM1
SCHEMBL1828068 0.77 KDM4E (0.38) DRD2DRD1PTGS2
SCHEMBL30203107 0.72 MAOB (0.35)
SCHEMBL20101404 0.72 TRPA1 (0.33) PNMT
SCHEMBL20825133 0.72 ALDH1A1 (0.42)
SCHEMBL28228041 0.72 ACHE (0.37) HTR5APNMTADRA2A
SCHEMBL12961127 0.71 GABRA1 (0.36) DRD2DRD3DRD4
SCHEMBL301029 0.71 NPC1 (0.41) HTR5ADRD2DRD3CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212535-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME Lg Chem, Ltd. (KR) 2023-07-19 EP disclosed