Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657361 | 0.76 | HTT (0.41) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9833467 | 0.72 | CDYL2 (0.48) | MEN1KMT2A | |
| SCHEMBL8655558 | 0.72 | DAO (0.36) | — | |
| SCHEMBL8653972 | 0.72 | CHRNB2 (0.36) | KMT2ASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL8657477 | 0.72 | TDP1 (0.37) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8653998 | 0.72 | CHRNB2 (0.36) | MAPK1 | |
| Ammonia Solution, Strong SCHEMBL27320686 | 0.71 | TDP1 (0.36) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27363938 | 0.71 | GAA (0.36) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15075740 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL27318754 | 0.68 | CCKBR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |