Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25318629 | 0.80 | PGR (0.38) | METADRA2BMEN1KMT2A | |
| SCHEMBL25315809 | 0.80 | PGR (0.38) | METADRA2BMEN1KMT2A | |
| SCHEMBL25908381 | 0.77 | HTR1A (0.41) | — | |
| SCHEMBL25908768 | 0.76 | ALK (0.38) | — | |
| SCHEMBL25933820 | 0.71 | TRIM24 (0.42) | MET | |
| SCHEMBL25316061 | 0.71 | SIGMAR1 (0.41) | MET | |
| SCHEMBL25316319 | 0.71 | SIGMAR1 (0.41) | MET | |
| SCHEMBL30507166 | 0.71 | SIGMAR1 (0.41) | MET | |
| SCHEMBL30506786 | 0.71 | SIGMAR1 (0.41) | MET | |
| SCHEMBL25909333 | 0.71 | IP6K1 (0.38) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |