SCHEMBL2592237

SCHEMBL2592237

NCC(=O)OCC(CO)(CO)CO

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7593286 0.95 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL7588073 0.87 MAPK1 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL4625213 0.80 MAPK1 (0.46) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL10973101 0.79 MEN1 (0.39)
SCHEMBL2096451 0.79 THRB (0.39) ALDH1A1MAPK1HIF1A
SCHEMBL9571839 0.77 MGAM (0.46) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL9325262 0.77 SERPINE1 (0.32)
SCHEMBL8342617 0.76 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL538388 0.76 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL11514839 0.76 CYP3A4 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION THERAGENICS CORPORATION 2019-08-29 US claimed
EP-2846847-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT Medicus Biosciences LLC (US) 2015-03-18 EP claimed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO claimed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US claimed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO claimed
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2023-07-13 US disclosed
EP-2968680-B1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION C P MEDICAL CORP (US) 2023-05-03 EP disclosed
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment AQUARIAN CREDIT FUNDING LLC 2023-03-07 US disclosed
US-20210322785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS THERAGENICS CORPORATION 2021-10-21 US disclosed
EP-3893785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS C.P. Medical Corporation (US) 2021-10-20 EP disclosed
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules C.P. MEDICAL CORPORATION (US) 2021-08-10 US disclosed
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2020-10-08 US disclosed
US-20140302051-A1 Biocompatible Hydrogel Polymer Formulations for the Controlled Delivery of Biomolecules MEDICUS BIOSCIENCES, LLC (US) 2014-10-09 US disclosed
WO-2014153004-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-25 WO disclosed
US-20140271528-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140248231-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES LLC (US) 2014-09-04 US disclosed
EP-2708224-A1 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules Medicus Biosciences LLC (US) 2014-03-19 EP disclosed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO disclosed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US disclosed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA ALDH1A1 297/4885TP53 2618/4885CYP3A4 4794/4885
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules HMGB1, HDGF, CRYAA ALDH1A1 661/4885TP53 409/4885CYP3A4 3749/4885
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA ALDH1A1 297/4885TP53 2618/4885CYP3A4 4794/4885
US-20140302051-A1 Biocompatible Hydrogel Polymer Formulations for the Controlled Delivery of Biomolecules HMGB1, HDGF, CRYAA ALDH1A1 661/4885TP53 409/4885CYP3A4 3749/4885
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 ALDH1A1 113/4885TP53 1767/4885CYP3A4 454/4885
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 ALDH1A1 84/4885TP53 1611/4885CYP3A4 339/4885
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA ALDH1A1 297/4885TP53 2618/4885CYP3A4 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.