SCHEMBL2596966

SCHEMBL2596966

CCO[Si](CCCC1=NOc2ccc(C#N)cc2C1)(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.31
DRD3 P35462 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596963 0.80 MAOA (0.31)
SCHEMBL2596954 0.70 MAOA (0.31)
SCHEMBL2596951 0.70 MAOA (0.31)
SCHEMBL10621715 0.61 MMP3 (0.38)
SCHEMBL253210 0.61 CYP2D6 (0.38) DRD2
SCHEMBL14226987 0.60 HTT (0.46)
SCHEMBL17442492 0.59 ALDH1A1 (0.36)
SCHEMBL23920288 0.59 CYP2A6 (0.39) DRD2DRD3
SCHEMBL3700876 0.58 PNMT (0.38) DRD2DRD3
SCHEMBL1473025 0.58 PTPRB (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593497-B1 SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS DOW SILICONES CORP (US) 2018-06-20 EP disclosed
US-9006372-B2 Silicone resins and their use in polymer compositions DOW CORNING (SHANGHAI) CO LTD (CN) 2015-04-14 US disclosed
US-20140303299-A1 Silicone Resins And Their Use in Polymers DOW CORNING CORPORATION 2014-10-09 US disclosed
EP-2780399-A2 SILICONE RESINS COMPRISING METALLOSILOXANE Dow Corning Corporation (US) 2014-09-24 EP disclosed
US-20140249257-A1 Silicone Resins Comprising Metallosiloxane DOW CORNING CORPORATION (US) 2014-09-04 US disclosed
WO-2013072370-A2 SILICONE RESINS COMPRISING METALLOSILOXANE DOW CORNING CORPORATION (US) 2013-05-23 WO disclosed
EP-2593496-A1 POLYMER COMPOSITIONS CONTAINING ALKOXYSILANES Dow Corning Corporation (US) 2013-05-22 EP disclosed
EP-2571937-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES Dow Corning Corporation (US) 2013-03-27 EP disclosed
US-20130065992-A1 Polymer Compositions Containing Oxazine-Based Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130065993-A1 Polymer Compositions Containing Alkoxysilanes DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
US-20130066009-A1 Silicone Resins And Their Use In Polymer Compositions DOW CORNING CORPORATION (US) 2013-03-14 US disclosed
WO-2011144575-A2 POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES DOW CORNING CORPORATION (US) 2011-11-24 WO disclosed
WO-2011143930-A1 POLYMER COMPOSITIONS CONTAINING ALKOXYSILANES DOW CORNING CORPORATIOM (US) 2011-11-24 WO disclosed