Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | TGM1 | P22735 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25987817 | 0.88 | ACHE (0.49) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL29255622 | 0.77 | CTSL (0.60) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL30456839 | 0.76 | CTSL (0.52) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL27922050 | 0.76 | CTSL (0.61) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL27922046 | 0.76 | CTSL (0.61) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL18342447 | 0.75 | CTSL (0.60) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL18342444 | 0.75 | CTSL (0.60) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL28805924 | 0.75 | OPRM1 (0.58) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL28805923 | 0.75 | OPRM1 (0.58) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL25367967 | 0.74 | CTSL (0.49) | CTSLCTSBCTSKEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202974-A1 | CASPASE 6 INHIBITORS AND USES THEREOF | CASP6, CASP1, CASP10 | CTSL 37/4885CTSB 117/4885CTSK 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.