Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341043 | 1.00 | TRPA1 (0.46) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7779594 | 0.83 | TRPA1 (0.46) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7756946 | 0.82 | TRPA1 (0.44) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7763374 | 0.81 | TRPA1 (0.46) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7760075 | 0.81 | TRPA1 (0.46) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7760073 | 0.81 | TRPA1 (0.42) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL7763332 | 0.81 | TRPA1 (0.42) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL14765434 | 0.80 | CTSL (0.51) | TRPA1TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL11633208 | 0.80 | TRPA1 (0.52) | TRPA1CYP2D6TSHRNPC1RAB9A | |
| SCHEMBL9028692 | 0.78 | ALDH1A1 (0.52) | TRPA1TSHRNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163933-B2 | Clean, high-yield preparation of S,S and R,S amino acid isosteres | AMPAC FINE CHEMICALS LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090012303-A1 | CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES | AEROJET FINE CHEMICALS LLC (US) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012303-A1 | CLEAN, HIGH-YIELD PREPARATION OF S,S AND R,S AMINO ACID ISOSTERES | SRMS, HCK, BHMT2 | TRPA1 4425/4885CYP2D6 1814/4885TSHR 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.