Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.61 |
| ▸ | CA2 | P00918 | 8/20 | 0.61 |
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA7 | P43166 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.61 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757531 | 0.82 | CES2 (0.65) | CES2LMNAMAPTPKMHPGD | |
| SCHEMBL2440560 | 0.82 | CA1 (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28450705 | 0.82 | MAPT (0.52) | CES2LMNAMAPTHPGDHTT | |
| SCHEMBL4587615 | 0.82 | CA1 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8900283 | 0.80 | LMNA (0.47) | CES2LMNAMAPTPKMHPGD | |
| SCHEMBL836180 | 0.80 | CES2 (0.62) | CA1CA2CES2LMNAMAPT | |
| SCHEMBL1943728 | 0.80 | HPGD (0.56) | CA1CA2CES2MAPTHPGD | |
| SCHEMBL12558164 | 0.80 | MAPK13 (0.45) | CES2MAPTHPGDHTTCES1 | |
| SCHEMBL2706993 | 0.80 | CES2 (0.62) | CA1CA2CES2LMNAMAPT | |
| SCHEMBL2122107 | 0.80 | CES2 (0.75) | CA1CA2CES2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497364-B2 | Compound for the determination of the protein FKBP12 and a sensor unit comprising it | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2025-12-16 | — | — | US | disclosed |
| WO-2025061176-A1 | CYCLOALKANE-SUBSTITUTED AMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海科技大学 | 2025-03-27 | — | — | WO | disclosed |
| CN-119661404-A | Cycloalkane substituted amine derivative, preparation method and application thereof | 上海科技大学 | 2025-03-21 | — | — | CN | disclosed |
| US-20230033380-A1 | A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2023-02-02 | — | — | US | disclosed |
| WO-2021124269-A1 | A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT | UNIVERSITÀ DEGLI STUDI DI FIRENZE (IT) | 2021-06-24 | — | — | WO | disclosed |
| US-20210095074-A1 | POLYOXAZOLIN WITH A PHOTOACTIVATABLE GROUP | BASF SE (DE) | 2021-04-01 | — | — | US | disclosed |
| EP-3649182-A1 | POLYOXAZOLIN WITH A PHOTOACTIVATABLE GROUP | BASF SE (DE) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019007803-A1 | POLYOXAZOLIN WITH A PHOTOACTIVATABLE GROUP | BASF SE (DE) | 2019-01-10 | — | — | WO | disclosed |
| US-20140206671-A1 | TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-07-24 | — | — | US | disclosed |
| US-20130090331-A1 | TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-04-11 | — | — | US | disclosed |
| US-5576343-A | ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0540051-B1 | Aromatic amidine derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0512352-B1 | Substituted carboxylic acid derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5344843-A | Carnitine acryltransferase enzyme inhibitors as antiischemic agents and for cardiovascular disorders | HOFFMAN-LA ROCHE INC. (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0414078-B1 | Disubstituted (quinolin-2-yl-methoxy)-phenylacetic acid derivatives | BAYER AG (DE) | 1994-06-01 | — | — | EP | disclosed |
| CN-1072677-A | Aromatic amidine derivative and salt thereof | DAIICHI SEIYAKU CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0540051-A1 | Aromatic amidine derivatives and salts thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5126354-A | LEUKOTRIENE SYNTHESIS-INHIBITING DISUBSTITUTED (QUINOLIN-2-YL-METHOXY) PHENYLACETIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| EP-0414078-A2 | Disubstituted (quinolin-2-yl-methoxy)-phenylacetic acid derivatives | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090331-A1 | TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASE | JAK2, JAK1, JAK3 | CA1 4802/4885CA2 4066/4885CA12 4716/4885 |
| US-12497364-B2 | Compound for the determination of the protein FKBP12 and a sensor unit comprising it | FKBP14, FKBP5, FKBP1A | CA1 169/4885CA2 1831/4885CA12 181/4885 |
| US-20230033380-A1 | A COMPOUND FOR THE DETERMINATION OF THE PROTEIN FKBP12 AND A SENSOR UNIT COMPRISING IT | FKBP14, FKBP1A, FKBP5 | CA1 231/4885CA2 2204/4885CA12 247/4885 |
| US-20140206671-A1 | TRICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF JANUS KINASE | JAK2, JAK1, JAK3 | CA1 4802/4885CA2 4066/4885CA12 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.