SCHEMBL3757531

SCHEMBL3757531

COC(=O)C(=O)c1ccc(C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.65
CES1 P23141 4/20 0.65
TDP1 Q9NUW8 2/20 0.61
ALDH1A1 P00352 7/20 0.56
MAPT P10636 2/20 0.56
KDM4E B2RXH2 1/20 0.56
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
LMNA P02545 2/20 0.52
GAA P10253 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PKM P14618 2/20 0.46
HTT P42858 2/20 0.46
ATM Q13315 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7991716 0.87 CES2 (0.60) CES2CES1TDP1ALDH1A1MAPT
SCHEMBL9043691 0.86 MAPT (0.59) CES2CES1TDP1ALDH1A1MAPT
SCHEMBL2601260 0.82 CA1 (0.61) CES2CES1TDP1ALDH1A1MAPT
SCHEMBL28450705 0.82 MAPT (0.52) CES2CES1ALDH1A1MAPTNPC1
SCHEMBL2440560 0.82 CA1 (0.61) TDP1ALDH1A1MAPTKDM4ENPC1
SCHEMBL4587615 0.82 CA1 (0.56) CES2CES1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL11469562 0.81 CYP2A6 (0.53) CES2CES1TDP1ALDH1A1MAPT
SCHEMBL836180 0.80 CES2 (0.62) CES2CES1ALDH1A1MAPTKDM4E
SCHEMBL12558164 0.80 MAPK13 (0.45) CES2CES1TDP1ALDH1A1MAPT
SCHEMBL8900283 0.80 LMNA (0.47) CES2CES1TDP1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070874-A1 BENZOYLFORMIC ACID AMIDE DERIVATIVE KJ CHEMICALS CORPORATION (JP) 2026-03-12 US disclosed
EP-4610249-A1 BENZOYLFORMIC ACID AMIDE DERIVATIVE KJ Chemicals Corporation (JP) 2025-09-03 EP disclosed
CN-119569569-A 1-Vinyl cyclobutene derivative and synthetic method and application thereof 南宁师范大学 2025-03-07 CN disclosed
WO-2024210074-A1 BENZOYLFORMIC ACID AMIDE DERIVATIVE KJケミカルズ株式会社 2024-10-10 WO disclosed
US-20240230687-A1 MASS TAGS FOR LIPID ANALYSES TEXAS A & M UNIV SYS (US) 2024-07-11 US disclosed
CN-111574425-A Novel benzoyl formic acid methyl ester photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-25 CN disclosed
CN-111559963-A Long-wavelength benzoyl formic acid methyl ester photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-21 CN disclosed
CN-111393291-A Novel synthesis method of α -carbonyl acid ester 宁波海曙琼杰化工技术研发工作室 2020-07-10 CN disclosed
EP-2231591-B1 METHOXYIMINO COMPOUNDS AND FUNGICIDE COMPOSITION COMPRISING SAME KYUNG NONG CORP (KR) 2015-02-11 EP disclosed
US-8410302-B2 Methoxyimino compounds and fungicide composition comprising same KYUNG NONG CORPORATION (KR) 2013-04-02 US disclosed
US-7455891-B2 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-11-25 US disclosed
US-20070128441-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
US-20070128441-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
EP-1200393-B1 OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2003-12-10 EP disclosed
EP-1200393-A1 OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY Monsanto Technology LLC (US) 2002-05-02 EP disclosed
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity MONSANTO TECHNOLOGY LLC. 2002-04-18 US disclosed
US-6359156-B1 CONTROLLING DISEASES IN CEREAL PLANTS MONSANTO TECHNOLOGY LLC 2002-03-19 US disclosed
US-6297271-B1 CONTROLLING TAKE-ALL DISEASE IN A PLANT MONSANTO TECHNOLOGY LLC 2001-10-02 US disclosed
WO-2001012590-A1 OXYME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2001-02-22 WO disclosed
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240230687-A1 MASS TAGS FOR LIPID ANALYSES MBOAT7, LIPC, PNLIP CES2 769/4885CES1 141/4885TDP1 2690/4885
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity AADAC, HAAO, OGA CES2 299/4885CES1 708/4885TDP1 2011/4885
US-20260070874-A1 BENZOYLFORMIC ACID AMIDE DERIVATIVE CRYAA, BCAT1, BRCA1 CES2 1111/4885CES1 945/4885TDP1 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.