Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901770 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNATNFKDM4ENPBWR1 | |
| SCHEMBL26163608 | 0.89 | ALDH1A1 (0.35) | SMN1; SMN2LMNAMMP1MMP9MMP8 | |
| SCHEMBL29382816 | 0.83 | NPBWR1 (0.41) | SMN1; SMN2LMNAMMP1MMP9MMP8 | |
| SCHEMBL21835495 | 0.83 | NPBWR1 (0.41) | SMN1; SMN2LMNAMMP1MMP9MMP8 | |
| SCHEMBL29761324 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAMMP1MMP9MMP8 | |
| SCHEMBL25202984 | 0.79 | HPGD (0.38) | SMN1; SMN2HPGDKDM4EKMT2ATDP1 | |
| SCHEMBL29383185 | 0.78 | HSD11B1 (0.38) | SMN1; SMN2HPGDNPBWR1ALDH1A1KMT2A | |
| SCHEMBL21835458 | 0.78 | HSD11B1 (0.38) | SMN1; SMN2HPGDNPBWR1ALDH1A1KMT2A | |
| SCHEMBL8210145 | 0.73 | KMT2A (0.47) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL21835554 | 0.72 | RAB9A (0.41) | SMN1; SMN2HPGDNPBWR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150945-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | CYP1B1, CHRM2, CYP1A1 | SMN1; SMN2 2651/4885LMNA 3876/4885MMP1 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.