Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26163609 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAKDM4ENPBWR1ALDH1A1 | |
| SCHEMBL26163608 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL29761324 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNANPBWR1KMT2AMAPT | |
| SCHEMBL29382816 | 0.72 | NPBWR1 (0.41) | SMN1; SMN2LMNANPBWR1ALDH1A1KMT2A | |
| SCHEMBL21835495 | 0.72 | NPBWR1 (0.41) | SMN1; SMN2LMNANPBWR1ALDH1A1KMT2A | |
| SCHEMBL20522633 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2LMNAKDM4ENPBWR1ALDH1A1 | |
| SCHEMBL29058636 | 0.70 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAKDM4ENPBWR1ALDH1A1 | |
| SCHEMBL11495787 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL10440127 | 0.67 | ALDH1A1 (0.56) | SMN1; SMN2LMNAALDH1A1KMT2AMAPT | |
| SCHEMBL25202984 | 0.67 | HPGD (0.38) | SMN1; SMN2KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202787-A1 | ATROPISOMERS OF PYRIDAZINONE DERIVATIVES AS HERBICIDES | FMC CORPORATION (US) | 2021-10-07 | — | — | WO | disclosed |