Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13382320 | 0.87 | MMP2 (0.48) | PDE5AHDAC1HDAC2TP53BP1 | |
| SCHEMBL6607450 | 0.86 | CASP3 (0.44) | TMPRSS15CASP3HDAC1HDAC2MYC | |
| SCHEMBL28088739 | 0.85 | GPR132 (0.52) | GPR132HDAC1HDAC2FOLH1ALB | |
| SCHEMBL26263203 | 0.85 | GPR132 (0.52) | GPR132HDAC1HDAC2FOLH1ALB | |
| SCHEMBL12620678 | 0.84 | HPGDS (0.55) | CA2CA1TMPRSS15CASP3PDE5A | |
| SCHEMBL13377443 | 0.83 | TP53BP1 (0.48) | HDAC1HDAC2TP53BP1MTORMYC | |
| SCHEMBL712931 | 0.82 | CA2 (0.65) | CA2CA1TMPRSS15CASP3 | |
| SCHEMBL697053 | 0.82 | CA2 (0.65) | CA2CA1TMPRSS15CASP3 | |
| SCHEMBL697052 | 0.82 | CA2 (0.65) | CA2CA1TMPRSS15CASP3 | |
| SCHEMBL5516521 | 0.82 | HDAC1 (0.45) | GPR132HDAC1HDAC2ALBIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183776-A2 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | UNIV NEW YORK (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | SUCNR1, SYNGR2, TSPO | CA2 2577/4885CA1 2837/4885TMPRSS15 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.