Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351174 | 0.90 | SLC2A1 (0.46) | BCHETYRACHELMNATSHR | |
| SCHEMBL4010346 | 0.89 | CA12 (0.48) | BCHETYRACHEKMT2AMAPT | |
| SCHEMBL16450355 | 0.88 | LMNA (0.44) | BCHETYRACHELMNAHIF1A | |
| SCHEMBL17189617 | 0.87 | HTR2A (0.42) | BCHETYRACHEKMT2AMAPT | |
| SCHEMBL4300089 | 0.85 | ADRA1A (0.40) | BCHETYRACHELMNATSHR | |
| SCHEMBL14416299 | 0.84 | THRA (0.47) | BCHETYRACHELMNATSHR | |
| SCHEMBL7524928 | 0.84 | THRA (0.47) | BCHETYRACHELMNAHIF1A | |
| SCHEMBL3145891 | 0.84 | THRA (0.57) | BCHETYRACHELMNATSHR | |
| SCHEMBL3507489 | 0.84 | THRA (0.57) | BCHETYRACHELMNATSHR | |
| SCHEMBL3507493 | 0.84 | THRA (0.57) | BCHETYRACHELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2017-05-18 | — | — | US | disclosed |
| US-9475837-B2 | Process for the synthesis of therapeutic peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2016-10-25 | — | — | US | disclosed |
| US-20150315243-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS | SYNGENE LTD (AU) | 2015-11-05 | — | — | US | disclosed |
| US-9102708-B2 | Methods for the synthesis of dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2015-08-11 | — | — | US | disclosed |
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2015-02-12 | — | — | US | disclosed |
| WO-2013093639-A1 | PROCESS FOR THE SYNTHESIS OF THERAPEUTIC PEPTIDES | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2013-06-27 | — | — | WO | disclosed |
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | SYNGENE LIMITED (AU) | 2013-05-16 | — | — | US | disclosed |
| US-8188217-B2 | — | — | 2012-05-29 | — | — | US | disclosed |
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | UNIVERSITE DE MONTREAL (CA) | 2012-04-26 | — | — | US | disclosed |
| US-8124726-B2 | Contoxin analogues and methods for synthesizing same | MONASH UNIVERSITY (AU) | 2012-02-28 | — | — | US | disclosed |
| US-7887845-B2 | Particle of a solid dispersion composed of a water soluble polymer and etravirine or salt thereof; etravirine FDA Orange book listed patent | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-15 | — | — | US | disclosed |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2010-07-08 | — | — | US | disclosed |
| US-7745573-B2 | Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides | POLYCHIP PHARMACEUTICALS PTY LTD. (AU) | 2010-06-29 | — | — | US | disclosed |
| US-7741280-B2 | Multimeric molecules, the preparation method thereof and use of same for the preparation of medicaments | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-22 | — | — | US | disclosed |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | MONASH UNIVERSITY (AU) | 2010-02-11 | — | — | US | disclosed |
| US-20100022749-A1 | Contoxin Analogues and Methods for Synthesizing Same | MONASH UNIVERSITY (AU) | 2010-01-28 | — | — | US | disclosed |
| US-7538190-B2 | Methods for the synthesis of two or more dicarba bridges in organic compounds | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 2009-05-26 | — | — | US | disclosed |
| US-20070197771-A1 | Methods for the synthesis of two or more dicarba bridges in organic compounds | SYNGENE LIMITED (AU) | 2007-08-23 | — | — | US | disclosed |
| US-20070197429-A1 | Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides | SYNGENE LIMITED (AU) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123463-A1 | METHODS FOR THE SYNTHESIS OF TWO OR MORE DICARBA BRIDGES IN ORGANIC COMPOUNDS | OTC, NBAS, IDH2 | BCHE 2320/4885TYR 1668/4885ACHE 2482/4885 |
| US-20100022749-A1 | Contoxin Analogues and Methods for Synthesizing Same | VIP, CANX, PDIA5 | BCHE 340/4885TYR 2022/4885ACHE 1085/4885 |
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | MAX, VIP, SFPQ | BCHE 2506/4885TYR 2578/4885ACHE 4732/4885 |
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | NPEPPS, DNPEP, QPCT | BCHE 2291/4885TYR 970/4885ACHE 4820/4885 |
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | QPCT, GLUL, ASNS | BCHE 266/4885TYR 2660/4885ACHE 1083/4885 |
| US-20100036089-A1 | Methods for the Synthesis of Dicarba Bridges in Organic Compounds | DCLRE1A, RNF168, MTCL3 | BCHE 896/4885TYR 1820/4885ACHE 1477/4885 |
| US-20150315243-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS | DCLRE1A, RNF168, MTCL3 | BCHE 896/4885TYR 1820/4885ACHE 1477/4885 |
| US-20070197771-A1 | Methods for the synthesis of two or more dicarba bridges in organic compounds | OTC, NBAS, IDH2 | BCHE 2320/4885TYR 1668/4885ACHE 2482/4885 |
| US-20070197429-A1 | Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides | VIP, NRDC, INHA | BCHE 640/4885TYR 3944/4885ACHE 2693/4885 |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | BCHE 3039/4885TYR 4353/4885ACHE 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.