SCHEMBL2641087

SCHEMBL2641087

CC(C)(C)c1cc(CCC(=O)O)cc(-n2nc3ccc(C(F)(F)F)cc3n2)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
FFAR4 Q5NUL3 3/20 0.38
FFAR1 O14842 5/20 0.37
MAOB P27338 2/20 0.37
PLA2G10 O15496 1/20 0.37
PLA2G2A P14555 1/20 0.37
PLA2G5 P39877 1/20 0.37
MAOA P21397 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
AGTR1 P30556 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KMT2A Q03164 2/20 0.36
NR1H4 Q96RI1 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
FFAR2 O15552 1/20 0.36
PDE5A O76074 1/20 0.36
PDE9A O76083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715026 0.92 GAA (0.38) GAAMAOBMAOAALDH1A1LMNA
SCHEMBL7530634 0.90 FFAR1 (0.39) FFAR4FFAR1PLA2G10PLA2G2APLA2G5
SCHEMBL16182319 0.90 FFAR1 (0.39) FFAR4FFAR1PLA2G10PLA2G2APLA2G5
SCHEMBL29353898 0.89 GAA (0.41) GAAMAOBMAOAALDH1A1LMNA
SCHEMBL768820 0.89 GAA (0.41) GAAMAOBMAOAALDH1A1LMNA
SCHEMBL5834423 0.88 GAA (0.39) GAAFFAR4FFAR1MAOBMAOA
SCHEMBL2637886 0.87 ALDH1A1 (0.35) GAAALDH1A1LMNAHTTSMN1; SMN2
SCHEMBL6861476 0.87 FFAR4 (0.37) FFAR4FFAR1PLA2G10PLA2G2APLA2G5
SCHEMBL14536574 0.86 GAA (0.40) GAAFFAR4MAOBMAOAALDH1A1
SCHEMBL100766 0.86 MAOB (0.45) GAAMAOBMAOAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
JP-4705249-B2 2011-06-22 JP claimed
EP-1789842-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-30 EP claimed
EP-1175467-B1 STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed
WO-2006005691-A1 STABILIZED ELECTROCHROMIC MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-19 WO claimed
EP-1252147-B1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-08-24 EP claimed
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 US claimed
JP-2005517787-A 2005-06-16 JP claimed
US-20050123691-A1 Photo-cured and stabilized coatings SUHADOLNIK JOSEPH (US) 2005-06-09 US claimed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 EP claimed
EP-1175467-A1 STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM Ciba SC Holding AG (CH) 2002-01-30 EP claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-6296674-B1 Candle wax stabilized with red-shift benzotriazoles CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-02 US claimed
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2001-09-20 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
WO-2001057125-A1 CANDLE WAX STABILIZED WITH RED-SHIFTED BENZOTRIAZOLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO claimed
US-6268415-B1 POLYMERS AND STABILIZERS FOR ENHANCED STABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-31 US claimed
US-6262151-B1 FOR AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 US claimed
WO-2000066676-A1 STABILIZED ADHESIVE COMPOSITIONS CONTAINING HIGHLY SOLUBLE, RED-SHIFTED, PHOTOSTABLE BENZOTRIAZOLE UV ABSORBERS AND LAMINATED ARTICLES DERIVED THEREFROM CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-11-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 GAA 1582/4885FFAR4 3402/4885FFAR1 3144/4885
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith FAAH, DBF4, TPH1 GAA 2324/4885FFAR4 75/4885FFAR1 328/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 GAA 1582/4885FFAR4 3402/4885FFAR1 3144/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 GAA 1582/4885FFAR4 3402/4885FFAR1 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.