SCHEMBL26413444

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24943664	0.90	OPRM1 (0.46)	OPRM1HDAC1F2LMNAHTR2A
	SCHEMBL26413775	0.87	ALDH1A1 (0.46)	OPRM1HDAC1F2LMNAOPRD1
	SCHEMBL24944313	0.87	ESR1 (0.42)	OPRM1HDAC1F2LMNAOPRD1
	SCHEMBL24943754	0.87	SMN1; SMN2 (0.43)	OPRM1HDAC1OPRD1OPRK1KCNH2
	SCHEMBL24944620	0.86	DRD2 (0.43)	OPRM1HDAC1TACR1DRD3KMT2A
	SCHEMBL26413644	0.86	PARP10 (0.44)	OPRM1HDAC1F2LMNAOPRD1
	SCHEMBL24944081	0.86	OPRM1 (0.44)	OPRM1HDAC1LMNAOPRD1OPRK1
	SCHEMBL24944860	0.86	OPRM1 (0.47)	OPRM1HDAC1OPRD1OPRK1KCNH2
	SCHEMBL24943674	0.86	NPC1 (0.43)	OPRM1HDAC1F2LMNAOPRD1
	SCHEMBL26478635	0.86	HDAC1 (0.41)	OPRM1HDAC1F2LMNAOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.