SCHEMBL26532564

SCHEMBL26532564

Cc1cnc(-c2ccc(C)c(-c3ccc(C#N)cc3C(F)(F)F)c2)cc1C

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 3/20 0.40
▸ CTSK P43235 3/20 0.40
▸ AR P10275 5/20 0.38
▸ NSD2 O96028 1/20 0.38
▸ FAAH O00519 4/20 0.38
▸ CYP11B2 P19099 2/20 0.38
▸ PTGDR2 Q9Y5Y4 1/20 0.38
▸ CYP11B1 P15538 1/20 0.38
▸ KIF11 P52732 1/20 0.36
▸ TRPV4 Q9HBA0 1/20 0.35
▸ SGK1 O00141 1/20 0.34
▸ ABL1 P00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26555715 0.84 KIF11 (0.46) CTSSCTSKARNSD2CYP11B2
SCHEMBL26532556 0.81 CYP11B2 (0.43) CTSKCYP11B2CYP11B1SGK1ABL1
SCHEMBL26532559 0.77 GRM5 (0.42) CTSKCYP11B2CYP11B1ABL1
SCHEMBL26627045 0.74 ALOX5AP (0.37) CTSSCTSKARCYP11B2CYP11B1
SCHEMBL26532554 0.73 ALOX5AP (0.40) KIF11ABL1
SCHEMBL7604551 0.73 TRPV4 (0.56) ARNSD2KIF11TRPV4
SCHEMBL26532558 0.72 RXRA (0.38) ABL1
SCHEMBL26627059 0.71 CYP11B2 (0.44) CYP11B2CYP11B1
SCHEMBL28668535 0.70 KIF11 (0.57) ARNSD2CYP11B2PTGDR2KIF11
SCHEMBL409405 0.70 TRPV4 (0.53) CTSSCTSKARPTGDR2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR CTSS 2790/4885CTSK 4067/4885AR 1049/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 CTSS 3803/4885CTSK 3151/4885AR 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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