SCHEMBL26555715

SCHEMBL26555715

Cc1ccc(-c2ccc(C)c(-c3ccc(C#N)cc3C(F)(F)F)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 2/20 0.46
▸ AR P10275 10/20 0.44
▸ TRPV4 Q9HBA0 1/20 0.40
▸ PTGDR2 Q9Y5Y4 1/20 0.40
▸ NSD2 O96028 1/20 0.38
▸ CTSS P25774 1/20 0.38
▸ CTSK P43235 1/20 0.38
▸ CYP11B2 P19099 2/20 0.37
▸ CYP11B1 P15538 1/20 0.37
▸ PGR P06401 1/20 0.36
▸ PDK2 Q15119 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532564 0.84 CTSS (0.40) KIF11ARTRPV4PTGDR2NSD2
SCHEMBL7604551 0.80 TRPV4 (0.56) KIF11ARTRPV4NSD2PDK2
SCHEMBL26532925 0.80 ALOX5AP (0.39) KIF11AR
SCHEMBL26555703 0.77 CYP11B2 (0.44) KIF11CTSKCYP11B2CYP11B1
SCHEMBL28668535 0.77 KIF11 (0.57) KIF11ARTRPV4PTGDR2NSD2
SCHEMBL409405 0.77 TRPV4 (0.53) KIF11ARTRPV4PTGDR2CTSS
SCHEMBL14499514 0.76 AR (0.48) KIF11ARCTSSCTSKPGR
SCHEMBL26652440 0.75 RXRA (0.46) KIF11ARPTGDR2CTSKCYP11B2
SCHEMBL14525154 0.75 AR (0.41) KIF11ARTRPV4NSD2CYP11B2
SCHEMBL25767772 0.74 CYP11B1 (0.45) CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 KIF11 3143/4885AR 829/4885TRPV4 745/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 KIF11 3067/4885AR 1225/4885TRPV4 330/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR KIF11 3154/4885AR 524/4885TRPV4 391/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR KIF11 3131/4885AR 506/4885TRPV4 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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