SCHEMBL26532925

SCHEMBL26532925

Cc1ccc(-c2ccc(C)c(-c3ccc(C(F)(F)F)cc3C(F)(F)F)c2)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 1/20 0.39
▸ FEN1 P39748 1/20 0.39
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ KIF11 P52732 1/20 0.38
▸ ABL1 P00519 1/20 0.37
▸ RXRA P19793 2/20 0.37
▸ RXRB P28702 2/20 0.37
▸ EDNRB P24530 1/20 0.37
▸ EDNRA P25101 1/20 0.37
▸ GLA P06280 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ NOTUM Q6P988 1/20 0.37
▸ CES2 O00748 1/20 0.37
▸ CYP2C9 P11712 1/20 0.36
▸ SCN9A Q15858 1/20 0.36
▸ AR P10275 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375442 0.87 NOTUM (0.45) ALOX5APFEN1KIF11ABL1GLA
SCHEMBL26532565 0.83 RXRA (0.41) TP53MAPTKIF11ABL1RXRA
SCHEMBL26532921 0.82 KIF11 (0.45) TP53MAPTKIF11ABL1RXRA
SCHEMBL26555715 0.80 KIF11 (0.46) KIF11AR
SCHEMBL20777524 0.79 S1PR1 (0.47) KIF11EDNRBEDNRACYP2C9SCN9A
SCHEMBL26375473 0.79 ALOX5AP (0.47) ALOX5APFEN1KIF11RXRARXRB
SCHEMBL26375492 0.79 ALOX5AP (0.47) ALOX5APFEN1EDNRBEDNRANOTUM
SCHEMBL10304774 0.77 KIF11 (0.54) TP53MAPTKIF11RXRARXRB
SCHEMBL28676412 0.77 TSHR (0.56) ALOX5APFEN1KIF11EDNRBEDNRA
SCHEMBL26532922 0.77 RXRB (0.51) TP53MAPTKIF11ABL1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 ALOX5AP 693/4885FEN1 3450/4885TP53 3893/4885
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR ALOX5AP 2375/4885FEN1 4130/4885TP53 4604/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR ALOX5AP 3174/4885FEN1 4546/4885TP53 3614/4885
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OPRM1, OSBP ALOX5AP 2317/4885FEN1 3079/4885TP53 4592/4885
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRM1, CHRM1 ALOX5AP 2671/4885FEN1 3330/4885TP53 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback