SCHEMBL26532922

SCHEMBL26532922

Cc1ccc(-c2ccc(C)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2)cc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRB P28702 5/20 0.51
▸ RXRA P19793 4/20 0.51
▸ RXRG P48443 3/20 0.48
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ KIF11 P52732 1/20 0.38
▸ PTGS2 P35354 2/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ ABL1 P00519 1/20 0.35
▸ RAPGEF4 Q8WZA2 1/20 0.35
▸ IKBKB O14920 1/20 0.35
▸ MCL1 Q07820 1/20 0.34
▸ AKR1C3 P42330 2/20 0.34
▸ AKR1C2 P52895 2/20 0.34
▸ NOTUM Q6P988 1/20 0.34
▸ HTR1A P08908 1/20 0.34
▸ HTR7 P34969 1/20 0.34
▸ PSEN1 P49768 1/20 0.33
▸ PSEN2 P49810 1/20 0.33
▸ APH1B Q8WW43 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26017262 0.92 RXRA (0.44) RXRBRXRARXRGTP53MAPT
SCHEMBL26532921 0.87 KIF11 (0.45) RXRBRXRARXRGTP53MAPT
SCHEMBL26652440 0.85 RXRA (0.46) RXRBRXRARXRGKIF11PSEN1
SCHEMBL26375444 0.83 NOTUM (0.46) RXRBRXRARXRGKIF11ABL1
SCHEMBL12665691 0.81 RXRA (0.42) RXRBRXRARXRGKIF11RAPGEF4
SCHEMBL26532565 0.81 RXRA (0.41) RXRBRXRARXRGTP53MAPT
SCHEMBL26532558 0.80 RXRA (0.38) RXRBRXRARXRGABL1IKBKB
SCHEMBL10304774 0.79 KIF11 (0.54) RXRBRXRARXRGTP53MAPT
SCHEMBL16574102 0.79 GPBAR1 (0.47) RXRBRXRARXRGRAPGEF4IKBKB
SCHEMBL26532925 0.77 ALOX5AP (0.39) RXRBRXRARXRGTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 RXRB 412/4885RXRA 361/4885RXRG 641/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 RXRB 1448/4885RXRA 1754/4885RXRG 1908/4885
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR RXRB 238/4885RXRA 326/4885RXRG 391/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR RXRB 307/4885RXRA 360/4885RXRG 590/4885
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OPRM1, OSBP RXRB 2154/4885RXRA 2654/4885RXRG 2651/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR RXRB 54/4885RXRA 82/4885RXRG 153/4885
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRM1, CHRM1 RXRB 1537/4885RXRA 2334/4885RXRG 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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