SCHEMBL26532565

SCHEMBL26532565

Cc1ccc(-c2ccc(C)c(-c3c(C(F)(F)F)cc(C(F)(F)F)cc3C(F)(F)F)c2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 2/20 0.41
▸ RXRB P28702 2/20 0.41
▸ RXRG P48443 1/20 0.38
▸ AR P10275 3/20 0.36
▸ TP53 P04637 2/20 0.36
▸ MAPT P10636 1/20 0.36
▸ KIF11 P52732 1/20 0.35
▸ PTGS2 P35354 4/20 0.33
▸ PTGS1 P23219 2/20 0.33
▸ ABL1 P00519 1/20 0.33
▸ TRPA1 O75762 1/20 0.33
▸ NOTUM Q6P988 2/20 0.32
▸ MCL1 Q07820 1/20 0.32
▸ S1PR1 P21453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26017268 0.89 AR (0.37) RXRARXRBARTP53MAPT
SCHEMBL26532925 0.83 ALOX5AP (0.39) RXRARXRBRXRGARTP53
SCHEMBL26627045 0.82 ALOX5AP (0.37) ARABL1TRPA1NOTUMS1PR1
SCHEMBL26532922 0.81 RXRB (0.51) RXRARXRBRXRGTP53MAPT
SCHEMBL26532921 0.80 KIF11 (0.45) RXRARXRBRXRGTP53MAPT
SCHEMBL26017262 0.77 RXRA (0.44) RXRARXRBRXRGTP53MAPT
SCHEMBL10304774 0.75 KIF11 (0.54) RXRARXRBRXRGTP53MAPT
SCHEMBL5936705 0.75 NOTUM (0.49) RXRARXRBARKIF11NOTUM
SCHEMBL5936706 0.73 NOTUM (0.47) RXRARXRBRXRGARKIF11
SCHEMBL26532927 0.72 APP (0.43) RXRARXRBTP53MAPTKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 RXRA 361/4885RXRB 412/4885RXRG 641/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 RXRA 1754/4885RXRB 1448/4885RXRG 1908/4885
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR RXRA 326/4885RXRB 238/4885RXRG 391/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR RXRA 360/4885RXRB 307/4885RXRG 590/4885
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OPRM1, OSBP RXRA 2654/4885RXRB 2154/4885RXRG 2651/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR RXRA 82/4885RXRB 54/4885RXRG 153/4885
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRM1, CHRM1 RXRA 2334/4885RXRB 1537/4885RXRG 2230/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 RXRA 894/4885RXRB 806/4885RXRG 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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