SCHEMBL26532927

SCHEMBL26532927

Cc1ccc(-c2ccc(F)c(-c3ccc(C(F)(F)F)cc3)c2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 2/20 0.43
▸ KIF11 P52732 6/20 0.42
▸ MAPT P10636 3/20 0.42
▸ TP53 P04637 2/20 0.42
▸ PTGS2 P35354 4/20 0.42
▸ PTGS1 P23219 2/20 0.41
▸ AKR1C3 P42330 1/20 0.40
▸ AKR1C2 P52895 1/20 0.40
▸ RXRA P19793 1/20 0.39
▸ RXRB P28702 1/20 0.39
▸ FFAR4 Q5NUL3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532921 0.88 KIF11 (0.45) APPKIF11MAPTTP53PTGS2
SCHEMBL10304774 0.84 KIF11 (0.54) KIF11MAPTTP53RXRARXRB
SCHEMBL26017275 0.82 PTGS2 (0.46) PTGS2PTGS1
SCHEMBL16906612 0.81 APP (0.46) APPKIF11MAPTAKR1C3AKR1C2
SCHEMBL26017270 0.81 PTGS2 (0.45) MAPTPTGS2PTGS1
SCHEMBL16906614 0.80 KIF11 (0.51) APPKIF11MAPTTP53PTGS2
SCHEMBL26532568 0.79 FEN1 (0.41) APPAKR1C3AKR1C2
SCHEMBL10064836 0.77 APP (0.50) APPKIF11AKR1C3AKR1C2FFAR4
SCHEMBL13471705 0.77 KIF11 (0.49) APPKIF11MAPTTP53PTGS2
SCHEMBL26532922 0.76 RXRB (0.51) KIF11MAPTTP53PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 APP 3188/4885KIF11 3143/4885MAPT 4205/4885
US-20230337516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LOXL1, OCIAD2, OGFRL1 APP 3428/4885KIF11 3067/4885MAPT 2216/4885
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR APP 4083/4885KIF11 3318/4885MAPT 3313/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR APP 4329/4885KIF11 3154/4885MAPT 3654/4885
US-20230337518-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OPRM1, OSBP APP 3902/4885KIF11 3379/4885MAPT 1563/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR APP 3501/4885KIF11 3131/4885MAPT 3040/4885
US-20230331755-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRM1, CHRM1 APP 3649/4885KIF11 2743/4885MAPT 3204/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 APP 3113/4885KIF11 1809/4885MAPT 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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