Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523492 | 0.83 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2D6NFKB1PNMT | |
| SCHEMBL265448 | 0.79 | LMNA (0.53) | CYP2D6ALDH1A1GAALMNAKMT2A | |
| SCHEMBL9630544 | 0.78 | ACP3 (0.41) | ADRB2ADRB1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10898417 | 0.78 | GABRA1 (0.54) | CYP3A4CYP1A2CYP2D6NFKB1ALDH1A1 | |
| SCHEMBL8863993 | 0.78 | HTT (0.40) | CYP3A4CYP1A2ALDH1A1GAALMNA | |
| SCHEMBL27496185 | 0.78 | ALDH1A1 (0.53) | CYP1A2ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL5066149 | 0.77 | ALDH1A1 (0.39) | ADRB2ADRB1CYP2D6NFKB1NISCH | |
| SCHEMBL943534 | 0.76 | MAPT (0.40) | CYP1A2ALDH1A1LMNAKMT2AHSP90AA1 | |
| SCHEMBL6029216 | 0.76 | L3MBTL1 (0.43) | ALDH1A1GAACNR1LMNAHPGD | |
| SCHEMBL265334 | 0.76 | ALDH1A1 (0.50) | CYP3A4CYP1A2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058707-C | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINA ACAD (CN) | 2000-11-22 | — | — | CN | claimed |
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-08-01 | — | — | US | disclosed |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-12-22 | — | — | US | disclosed |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-09-27 | — | — | US | disclosed |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-09-24 | — | — | US | disclosed |
| US-7288500-B2 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS HEAVY OIL, LLC | 2007-03-01 | — | — | US | disclosed |
| EP-0842920-B1 | Process for the production of aromatic halogen-amino compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-07 | — | — | EP | disclosed |
| US-6197716-B1 | AS HYDROGENATION CATALYST IN HYDROGENATION OF AROMATIC HALONITRO COMPOUNDS TO AROMATIC HALOAMINO COMPOUNDS | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |
| CN-1058707-C | Process for synthesis of d1-trans-4-phenyl-5-0-chlorobenzyl-pyrrolidone-2 | KUNMING PLANTS INST CHINA ACAD (CN) | 2000-11-22 | — | — | CN | disclosed |
| EP-0842920-A2 | Process for the production of aromatic halogen-amino compounds | Novartis AG (CH) | 1998-05-20 | — | — | EP | disclosed |
| US-4020107-A | ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR | E. I. DU PONT DE NEMOURS AND CO. (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | ARG2, NDUFS5, NDUFS7 | ADRB2 309/4885ADRB1 395/4885CYP3A4 587/4885 |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | ARG2, NDUFS5, NDUFS7 | ADRB2 309/4885ADRB1 395/4885CYP3A4 587/4885 |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | ARG2, NOS2, NDUFS7 | ADRB2 247/4885ADRB1 396/4885CYP3A4 1219/4885 |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | ARG2, NOS2, NDUFS7 | ADRB2 247/4885ADRB1 396/4885CYP3A4 1219/4885 |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | NOXO1, PYM1, HCN4 | ADRB2 342/4885ADRB1 349/4885CYP3A4 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.