Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600423 | 0.94 | ALDH1A1 (0.67) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1425163 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2671247 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24860844 | 0.85 | TAS1R3 (0.44) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2670654 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2670740 | 0.85 | TAS1R3 (0.47) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16706128 | 0.84 | KDM5A (0.53) | ALDH1A1KDM4EHSD17B10KDM5ACA12 | |
| SCHEMBL15535692 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10KDM5ACA12 | |
| SCHEMBL15535176 | 0.82 | TDP1 (0.47) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2671085 | 0.80 | S1PR1 (0.38) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015743-A1 | MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS | WISCONSIN ALUMNI RES FOUND (US) | 2026-01-15 | — | — | US | disclosed |
| US-11760751-B2 | Benzo 2-azaspiro[4.4]nonane compound and use thereof | HELIOEAST SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2023-09-19 | — | — | US | disclosed |
| US-11760751-B2 | Benzo 2-azaspiro[4.4]nonane compound and use thereof | HELIOEAST SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2023-09-19 | — | — | US | disclosed |
| US-20230126480-A1 | BENZO 2-AZASPIRO[4.4]NONANE COMPOUND AND USE THEREOF | HELIOEAST PHARMACEUTICAL CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230126480-A1 | BENZO 2-AZASPIRO[4.4]NONANE COMPOUND AND USE THEREOF | HELIOEAST PHARMACEUTICAL CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| EP-4116294-A1 | BENZO 2-AZASPIRO[4.4]NONANE COMPOUND AND USE THEREOF | HELIOEAST PHARMACEUTICAL CO., LTD. (CN) | 2023-01-11 | — | — | EP | disclosed |
| US-11192886-B2 | S1P1 agonist and application thereof | MEDSHINE DISCOVERY INC. (CN) | 2021-12-07 | — | — | US | disclosed |
| US-20210300908-A1 | S1P1 AGONIST AND APPLICATION THEREOF | Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) | 2021-09-30 | — | — | US | disclosed |
| EP-3492465-B1 | S1P1 AGONIST AND APPLICATION THEREOF | SHIJIAZHUANG SAGACITY NEW DRUG DEV CO LTD (CN) | 2021-03-24 | — | — | EP | disclosed |
| US-9133179-B2 | 2-methoxy-pyridin-4-yl-derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-09-15 | — | — | US | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| CN-102471328-B | Pyridin-4-yl derivatives | ACTELION PHARMACEUTICALS LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8658675-B2 | Pyridin-4-yl derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-02-25 | — | — | US | disclosed |
| EP-2665720-A1 | 2-METHOXY-PYRIDIN-4-YL DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2013-11-27 | — | — | EP | disclosed |
| US-20130303514-A1 | 2-METHOXY-PYRIDIN-4-YL-DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-11-14 | — | — | US | disclosed |
| EP-2454255-B1 | PYRIDIN-4-YL DERIVATIVES AS S1P1/EDG1 AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012098505-A1 | 2-METHOXY-PYRIDIN-4-YL DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-26 | — | — | WO | disclosed |
| EP-2454255-A1 | PYRIDIN-4-YL DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2012-05-23 | — | — | EP | disclosed |
| US-20120108638-A1 | PYRIDIN-4-YL DERIVATIVES | VIATRIS ASIA PACIFIC PTE. LTD. (SG) | 2012-05-03 | — | — | US | disclosed |
| WO-2011007324-A1 | PYRIDIN-4-YL DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192886-B2 | S1P1 agonist and application thereof | S1PR1, S1PR2, S1PR3 | ALDH1A1 2418/4885KDM4E 3986/4885TAS1R3 1509/4885 |
| US-20120108638-A1 | PYRIDIN-4-YL DERIVATIVES | CD4, IL4, FCGRT | ALDH1A1 958/4885KDM4E 629/4885TAS1R3 2970/4885 |
| US-20260015743-A1 | MEDIATED HYDROGEN ANODE FOR USE IN REDUCTIVE ELECTROSYNTHESIS | HAO2, HACL2, HVCN1 | ALDH1A1 246/4885KDM4E 3823/4885TAS1R3 3552/4885 |
| US-20130303514-A1 | 2-METHOXY-PYRIDIN-4-YL-DERIVATIVES | CD4, IL2, IL4 | ALDH1A1 797/4885KDM4E 271/4885TAS1R3 3493/4885 |
| US-20230126480-A1 | BENZO 2-AZASPIRO[4.4]NONANE COMPOUND AND USE THEREOF | AZI2, GABBR2, CNDP2 | ALDH1A1 284/4885KDM4E 547/4885TAS1R3 3841/4885 |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | IMPDH1, IMPDH2, ITPA | ALDH1A1 631/4885KDM4E 1225/4885TAS1R3 4460/4885 |
| US-11760751-B2 | Benzo 2-azaspiro[4.4]nonane compound and use thereof | AZI2, GABBR2, CNDP2 | ALDH1A1 284/4885KDM4E 547/4885TAS1R3 3841/4885 |
| US-20210300908-A1 | S1P1 AGONIST AND APPLICATION THEREOF | S1PR1, S1PR2, S1PR3 | ALDH1A1 2418/4885KDM4E 3986/4885TAS1R3 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.