Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637341 | 0.80 | SIGMAR1 (0.33) | HTR4OPRM1OPRD1SIGMAR1HRH3 | |
| SCHEMBL4342319 | 0.78 | LTA4H (0.36) | LTA4HHRH3ACHEGAA | |
| SCHEMBL6530435 | 0.78 | NCF1 (0.46) | HTR4OPRM1SIGMAR1HRH3ADRA2A | |
| SCHEMBL2677452 | 0.78 | HTR4 (0.33) | HTR4OPRM1OPRD1SIGMAR1HRH3 | |
| SCHEMBL4502994 | 0.77 | KCNA3 (0.35) | OPRM1OPRD1SIGMAR1RAB9AHRH3 | |
| SCHEMBL2676354 | 0.76 | CYP2D6 (0.44) | LTA4HSIGMAR1RAB9ANPC1ADRA2C | |
| SCHEMBL9471641 | 0.76 | CYP2D6 (0.44) | LTA4HSIGMAR1RAB9ANPC1ADRA2C | |
| Methane SCHEMBL2677973 | 0.76 | MAPT (0.35) | OPRM1OPRD1SIGMAR1RAB9AHRH3 | |
| SCHEMBL12718253 | 0.75 | HTR4 (0.39) | HTR4OPRM1OPRD1SIGMAR1RAB9A | |
| SCHEMBL24243286 | 0.75 | OPRD1 (0.38) | OPRM1OPRD1SIGMAR1HRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (JP) | 2012-05-03 | — | — | US | disclosed |
| WO-2001014381-A1 | ETHER DERIVATIVES OF PYRROLO[1,2-A]QUINOXALINES, METHOD FOR PRODUCING THEM AND THEIR USE IN THERAPY | UNIVERSITE DE CAEN BASSE-NORMANDIE (FR) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | BCHE, ACHE, SMPD1 | LTA4H 205/4885HTR4 2119/4885OPRM1 3784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.