Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877216 | 0.88 | NCF1 (0.39) | NCF1CXCR4HTR4DRD2DRD3 | |
| SCHEMBL7637341 | 0.80 | SIGMAR1 (0.33) | HTR4MAPTHRH3ADRA2AADRA2B | |
| SCHEMBL2677971 | 0.78 | LTA4H (0.36) | HTR4MAPTHRH3ADRA2AADRA2B | |
| SCHEMBL2677452 | 0.78 | HTR4 (0.33) | HTR4MAPTHRH3ADRA2AADRA2B | |
| SCHEMBL3342324 | 0.77 | GNAI3 (0.39) | HTR4MAPTHRH3ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL19462371 | 0.77 | NCF1 (0.45) | NCF1CXCR4LMNAPLGPLAT | |
| SCHEMBL12718253 | 0.75 | HTR4 (0.39) | HTR4HRH3DRD2DRD3SIGMAR1 | |
| SCHEMBL24243286 | 0.75 | OPRD1 (0.38) | MAPTHRH3ADRA2AADRA2BADRA2C | |
| SCHEMBL4959156 | 0.75 | SIGMAR1 (0.35) | MAPTHRH3ADRA2AADRA2BADRA2C | |
| SCHEMBL4502992 | 0.75 | SIGMAR1 (0.35) | HTR4MAPTHRH3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005194197-A | METHOD FOR PRODUCING 1-ALKYL-4-AMINOMETHYLPIPERIDINE | KOEI CHEM CO LTD | 2005-07-21 | — | — | JP | disclosed |