SCHEMBL268601

SCHEMBL268601

COC(=O)c1cc(O)ccc1N

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.67
CA1 P00915 5/20 0.67
CA2 P00918 5/20 0.67
CA7 P43166 5/20 0.67
CA9 Q16790 5/20 0.67
CA14 Q9ULX7 5/20 0.67
ALDH1A1 P00352 6/20 0.64
KDM4E B2RXH2 6/20 0.64
GAA P10253 6/20 0.64
HSD17B10 Q99714 4/20 0.64
MAPT P10636 3/20 0.64
HPGD P15428 3/20 0.64
ALOX15 P16050 2/20 0.64
TSHR P16473 2/20 0.64
PDK2 Q15119 1/20 0.61
PDK4 Q16654 1/20 0.61
CFTR P13569 3/20 0.58
GLA P06280 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4826905 0.85 ALDH1A1 (0.68) CA12CA1CA2CA7CA9
SCHEMBL267307 0.83 KDM4E (0.62) CA1CA2ALDH1A1KDM4EGAA
SCHEMBL7529190 0.82 KDM4E (0.66) CA12CA1CA2CA7CA9
SCHEMBL6168887 0.82 GAA (0.66) CA12CA1CA2CA7CA9
SCHEMBL19169070 0.82 KDM4E (0.49) CA12CA1CA2CA7CA9
SCHEMBL158999 0.82 CA12 (0.74) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL5100210 0.81 ALDH1A1 (0.60) CA1CA2ALDH1A1KDM4EGAA
SCHEMBL2746519 0.81 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL1129416 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EGAAHSD17B10MAPT
SCHEMBL2912873 0.81 KDM4E (0.73) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154095-A1 SYNTHESIS METHOD OF AVENANTHRAMIDE C DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION (KR) 2025-05-15 US claimed
CN-116730657-B Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-07-12 CN claimed
CN-117925335-A Semiconductor titanium nitride cleaning solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2024-04-26 CN claimed
CN-116730657-A Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-09-12 CN claimed
WO-2023140435-A1 METHOD FOR SYNTHESIZING AVENANTHRAMIDES C 동아대학교 산학협력단 2023-07-27 WO claimed
CN-116377715-A High-elasticity ultraviolet-resistant fabric and preparation method thereof 盐城市金达纺织有限公司 2023-07-04 CN claimed
US-12594277-B2 Macrocyclic ULK1/2 inhibitors SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-04-07 US disclosed
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2026-01-22 US disclosed
US-20250326713-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-10-23 US disclosed
US-20250312362-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-10-09 US disclosed
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
EP-4584258-A1 RAPIDLY ACCELERATED FIBROSARCOMA (RAF) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE Arvinas Operations, Inc. (US) 2025-07-16 EP disclosed
CN-120137338-A Anti-aging polypropylene material and preparation method thereof 南通金威复合材料有限公司 2025-06-13 CN disclosed
EP-0638075-B1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMA CO LTD (JP) 2002-01-16 EP disclosed
WO-2001009093-A1 BENZENAMINE DERIVATIVES AS ANTI-COAGULANTS BERLEX LABORATORIES, INC. (US) 2001-02-08 WO disclosed
EP-0855387-A1 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
US-5677322-A THERAPY FOR AGING, DIABETES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-10-14 US disclosed
US-5532138-A Method and kits for determining peroxidatively active catalysts BEHRINGWERKE AG (DE) 1996-07-02 US disclosed
EP-0638075-A1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-02-15 EP disclosed
WO-1994019335-A1 THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594277-B2 Macrocyclic ULK1/2 inhibitors ULK1, ULK2, ULK3 CA12 4504/4885CA1 4726/4885CA2 3061/4885
US-20250154095-A1 SYNTHESIS METHOD OF AVENANTHRAMIDE C OAT, MCCC2, OTC CA12 408/4885CA1 602/4885CA2 500/4885
US-20250312362-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MSRB3, ABCC1, MRPS34 CA12 4275/4885CA1 4753/4885CA2 2766/4885
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 CA12 4778/4885CA1 4417/4885CA2 4744/4885
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, NR1H4, CNR1 CA12 4257/4885CA1 2945/4885CA2 3205/4885
US-20250326713-A1 INHIBITORS OF MsbA AS ANTIBIOTICS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MSRB3, ARSA, ABCG2 CA12 4654/4885CA1 4834/4885CA2 2632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.