SCHEMBL2687669

SCHEMBL2687669

C[C@@H](O[Si](C)(C)C(C)(C)C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2686923 1.00 TP53 (0.32) TP53
SCHEMBL840126 1.00 TP53 (0.32) TP53
SCHEMBL1369677 0.82
SCHEMBL13413224 0.82
SCHEMBL13413222 0.82
SCHEMBL25176906 0.80 APLNR (0.31)
SCHEMBL19260399 0.80
SCHEMBL15717701 0.80 APLNR (0.31)
SCHEMBL8221420 0.80 APLNR (0.31)
SCHEMBL8823309 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304523-A1 COMBINED LACTATE AND KETONE BODY ESTERS FOR MEDICAL AND NUTRITIONAL USE AARHUS UNIVERSITET (DK) 2025-10-02 US disclosed
EP-4583867-A2 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE Latigo Biotherapeutics, Inc. (US) 2025-07-16 EP disclosed
US-20250154109-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE LATIGO BIOTHERAPEUTICS, INC 2025-05-15 US disclosed
CN-119894509-A Sodium channel blocking compounds, derivatives thereof, and methods of use thereof 拉堤果生物医疗股份有限公司 2025-04-25 CN disclosed
EP-4519239-A1 COMBINED LACTATE AND KETONE BODY ESTERS FOR MEDICAL AND NUTRITIONAL USE Aarhus Universitet (DK) 2025-03-12 EP disclosed
WO-2025029890-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE LATIGO BIOTHERAPEUTICS, INC. (US) 2025-02-06 WO disclosed
CN-119212974-A Combination lactic acid and ketoesters for medical and nutritional use 奥胡斯大学 2024-12-27 CN disclosed
EP-4472966-A2 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE Latigo Biotherapeutics, Inc. (US) 2024-12-11 EP disclosed
US-20240139158-A1 METHODS OF TREATING PULMONARY DISEASES AND DISORDERS PROTEOSTASIS THERAPEUTICS INC (US) 2024-05-02 US disclosed
US-20240116878-A1 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2024-04-11 US disclosed
US-8168648-B2 Camptothecin derivatives and uses thereof TAIWAN LIPOSOME CO., LTD. (TW) 2012-05-01 US disclosed
US-20100227877-A1 NEW CAMPTOTHECIN DERIVATIVES AND USES THEREOF TAIWAN LIPOSOME CO. LTD. (TW) 2010-09-09 US disclosed
US-20100227877-A1 NEW CAMPTOTHECIN DERIVATIVES AND USES THEREOF TAIWAN LIPOSOME CO. LTD. (TW) 2010-09-09 US disclosed
US-7582781-B2 epoxidation to produce 1,2-Epoxy-2-(2,4-difluorophenyl)butan-3-ol intermediate for pharmaceutical drugs, a triazole antifungal agent KANEKA CORPORATION (JP) 2009-09-01 US disclosed
EP-1475370-B1 OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS INC (JP) 2009-08-05 EP disclosed
US-7271185-B2 Optically active azole derivative and process for producing the same MITSUI CHEMICALS, INC. (JP) 2007-09-18 US disclosed
US-20060155136-A1 Optically active halohydrin derivative and process for producing optically active epoxy alcohol derivative from the same KANEKA CORPORATION (JP) 2006-07-13 US disclosed
EP-1647551-A1 OPTICALLY ACTIVE HALOHYDRIN DERIVATIVE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE EPOXY ALCOHOL DERIVATIVE FROM THE SAME KANEKA CORPORATION (JP) 2006-04-19 EP disclosed
US-20050085521-A1 Optically active azole derivative and process for producing the same MITSUI CHEMICALS, INC. (JP) 2005-04-21 US disclosed
EP-1475370-A1 OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Mitsui Chemicals, Inc. (JP) 2004-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154109-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE SCN8A, TRPV1, SCNN1A TP53 4831/4885
US-20060155136-A1 Optically active halohydrin derivative and process for producing optically active epoxy alcohol derivative from the same TALDO1, CYP51A1, ERG28 TP53 4710/4885
US-20050085521-A1 Optically active azole derivative and process for producing the same ADH1C, ADH1A, ADH5 TP53 4538/4885
US-20240116878-A1 2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS PTPN5, PTPN2, PTPN22 TP53 241/4885
US-20250304523-A1 COMBINED LACTATE AND KETONE BODY ESTERS FOR MEDICAL AND NUTRITIONAL USE LDHB, LDHA, LCT TP53 1240/4885
US-20240139158-A1 METHODS OF TREATING PULMONARY DISEASES AND DISORDERS SMPD1, ELANE, SMPD2 TP53 4251/4885
US-20100227877-A1 NEW CAMPTOTHECIN DERIVATIVES AND USES THEREOF LDHA, LDHB, TOP2A TP53 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.