Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263221 | 0.78 | ALDH1A1 (0.47) | HSP90AA1HSP90AB1PNLIPALDH1A1LMNA | |
| SCHEMBL23263219 | 0.72 | SOS1 (0.50) | HSP90AA1HSP90AB1HSPB1DAOSOS1 | |
| SCHEMBL20034244 | 0.70 | ALDH1A1 (0.44) | HSP90AA1HSP90AB1HSPB1PNLIPSOS1 | |
| SCHEMBL522433 | 0.69 | ESR1 (0.74) | HSPB1SOS1MEN1KMT2AGAA | |
| SCHEMBL23263868 | 0.68 | L3MBTL1 (0.46) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL6805040 | 0.67 | LTA4H (0.48) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL29084741 | 0.67 | PNLIP (0.47) | HSP90AA1PNLIPNPBWR1MCHR1LMNA | |
| SCHEMBL28374724 | 0.67 | NPC1 (0.58) | PNLIPSOS1ALDH1A1LMNAPDE4A | |
| SCHEMBL22966254 | 0.67 | HSPB1 (0.47) | HSPB1SOS1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6289867 | 0.66 | SOS1 (0.58) | HSPB1SOS1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | KINESID THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018105-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | TXNRD2, TXNRD1, SDHB | HSP90AA1 568/4885HSP90AB1 317/4885HSPB1 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.