Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | ITGB3 known ✓ | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B known ✓ | P08514 | 3/20 | 0.32 |
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL158122 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL27080 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL502962 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822489 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Water SCHEMBL6822493 | 1.00 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178169 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL29136617 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL178168 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| SCHEMBL786150 | 0.98 | ECE1 (0.40) | ECE1PLA2G2AKMT2ANPSR1ADRA1A | |
| Hydrochloric Acid SCHEMBL6055023 | 0.96 | ECE1 (0.39) | ECE1PLA2G2AKMT2ANPSR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139088-A1 | PROCESS FOR PREPARATION OF MONODISPERSE PARTICLES | N-lab Technology Center Pte, Ltd. (SG) | 2026-05-21 | — | — | US | claimed |
| EP-4146381-B1 | SUPERPARAMAGNETIC MONODISPERSE PARTICLES AND METHOD FOR THE PRODUCTION THEREOF | N LAB TECH CENTER PTE LTD (SG) | 2026-04-08 | — | — | EP | claimed |
| EP-3901181-B1 | METHOD FOR PRODUCING POLYVINYLPHOSPHONIC ACID COPOLYMER | MARUZEN PETROCHEM CO LTD (JP) | 2026-02-18 | — | — | EP | claimed |
| CN-119708343-A | Disulfonate hydrophobically associating polymer oil displacement agent with cyclic structure and preparation method thereof | 河北石油职业技术大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119708342-A | Disulfonate hydrophobically associating polymer oil displacement agent with benzene ring structure and preparation method thereof | 河北石油职业技术大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119708345-A | Betaine type hydrophobically associating polymer oil displacement agent with cyclic structure and preparation method thereof | 河北石油职业技术大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119661772-A | Betaine type double-tail hydrophobic association polymer fracturing thickener and preparation method thereof | 河北石油职业技术大学 | 2025-03-21 | — | — | CN | claimed |
| CN-119570362-A | Stain-proofing member, member for in vitro diagnostic device, and method for producing stain-proofing member | 佳能株式会社 | 2025-03-07 | — | — | CN | claimed |
| CN-119505078-A | Double-tail hydrophobically associating polymer oil displacement agent with annular structure and preparation method thereof | 河北石油职业技术大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119505080-A | Cyclic betaine and double-tail hydrophobic association polymer fracturing thickener and preparation method thereof | 河北石油职业技术大学 | 2025-02-25 | — | — | CN | claimed |
| US-20130292611-A1 | HYBRID MIXTURES FOR GAS HYDRATE INHIBITION APPLICATIONS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2013-11-07 | — | — | US | claimed |
| EP-2658945-A1 | HYBRID MIXTURES FOR GAS HYDRATE INHIBITION APPLICATIONS | Akzo Nobel Chemicals International B.V. (NL) | 2013-11-06 | — | — | EP | claimed |
| WO-2012089654-A1 | HYBRID MIXTURES FOR GAS HYDRATE INHIBITION APPLICATIONS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2012-07-05 | — | — | WO | claimed |
| US-20120107737-A1 | Toner Compositions | XEROX CORPORATION (US) | 2012-05-03 | — | — | US | claimed |
| US-8092972-B2 | Toner compositions | XEROX CORPORATION (US) | 2012-01-10 | — | — | US | claimed |
| US-20100055592-A1 | TONER COMPOSITIONS | XEROX CORPORATION (US) | 2010-03-04 | — | — | US | claimed |
| EP-2159643-A1 | Toner composition and method of preparation | Xerox Corporation (US) | 2010-03-03 | — | — | EP | claimed |
| EP-2010556-A4 | HOMOGENEOUS ERYTHROPOIETIN AND OTHER PEPTIDES AND PROTEINS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION | SLOAN KETTERING INST CANCER (US) | 2009-09-02 | — | — | EP | claimed |
| EP-2010556-A2 | HOMOGENEOUS ERYTHROPOIETIN AND OTHER PEPTIDES AND PROTEINS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION | Sloan-Kettering Institute for Cancer Research (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007120614-A2 | HOMOGENEOUS ERYTHROPOIETIN AND OTHER PEPTIDES AND PROTEINS, METHODS AND INTERMEDIATES FOR THEIR PREPARATION | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2007-10-25 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139088-A1 | PROCESS FOR PREPARATION OF MONODISPERSE PARTICLES | CD14, CD47, MYD88 | ADRA1A 2517/4885ITGB3 188/4885ITGA2B 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.