Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 3/20 | 0.32 |
| ▸ | SDC2 | P34741 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25742155 | 0.75 | LMNA (0.42) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL29691298 | 0.74 | USP1 (0.41) | MEN1KMT2AMAPTITGB3ITGA2B | |
| SCHEMBL18865618 | 0.74 | USP1 (0.41) | MEN1KMT2AMAPTITGB3ITGA2B | |
| SCHEMBL16193397 | 0.73 | ALOX15 (0.41) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL23482963 | 0.73 | MAPT (0.39) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25741843 | 0.73 | SDCBP (0.35) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL24692214 | 0.71 | ITGB3 (0.38) | MEN1KMT2AMAPTITGB3ITGA2B | |
| SCHEMBL22906808 | 0.70 | ALOX15 (0.33) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL23665116 | 0.68 | KCNH2 (0.46) | MEN1KMT2AALOX15MAPTSMN1; SMN2 | |
| SCHEMBL17517148 | 0.68 | KCNH2 (0.40) | MEN1KMT2AALOX15MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201282-A1 | NOVEL GSPT1 COMPOUNDS AND METHODS OF USE OF THE NOVEL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-19 | — | — | WO | disclosed |