Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928515 | 0.81 | ALDH1A1 (0.62) | LMNACES2CES1KMT2AALDH1A1 | |
| SCHEMBL2732048 | 0.81 | KMT2A (0.60) | CA2LMNAKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL810 | 0.79 | KMT2A (0.58) | CA2LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL3353838 | 0.76 | CA2 (0.57) | CA2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL594 | 0.76 | CA2 (0.53) | CA2KMT2AALDH1A1MEN1GAA | |
| SCHEMBL5444394 | 0.76 | CA2 (0.53) | CA2LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL7326944 | 0.76 | LMNA (0.53) | LMNACES2CES1KMT2AALDH1A1 | |
| SCHEMBL5483965 | 0.76 | LMNA (0.53) | LMNACES2CES1KMT2AALDH1A1 | |
| SCHEMBL27575403 | 0.74 | MEN1 (0.54) | CA2LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL1395462 | 0.74 | LMNA (0.52) | LMNACES2CES1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135773-A1 | Trisubstituted nitrogen modulators of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135773-A1 | Trisubstituted nitrogen modulators of tyrosine phosphatases | PTPA, PTPN1, PTPRS | CA2 2306/4885LMNA 4794/4885CES2 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.