⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537561 | 0.84 | LMNA (0.33) | — | |
| SCHEMBL9241622 | 0.81 | ACKR3 (0.32) | — | |
| SCHEMBL8537910 | 0.80 | NCF1 (0.34) | — | |
| SCHEMBL9243159 | 0.78 | — | — | |
| SCHEMBL27340761 | 0.69 | NCF1 (0.34) | — | |
| SCHEMBL8539150 | 0.65 | ADRA2A (0.39) | — | |
| SCHEMBL16093682 | 0.61 | L3MBTL1 (0.39) | — | |
| SCHEMBL8540389 | 0.60 | LMNA (0.38) | — | |
| SCHEMBL23475665 | 0.57 | BCAT1 (0.46) | — | |
| SCHEMBL10458618 | 0.55 | ADRA1D (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657450-A1 | INDAZOLESULFONYLUREA DERIVATIVE, USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KumaiI Chemical Industry Co., Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |