Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367313 | 0.78 | CCKBR (0.38) | FAAHNPC1RAB9AMCHR1 | |
| SCHEMBL15964717 | 0.71 | RIPK1 (0.42) | — | |
| SCHEMBL19980166 | 0.66 | RIPK1 (0.34) | — | |
| SCHEMBL17538292 | 0.65 | PDK1 (0.31) | — | |
| SCHEMBL958441 | 0.65 | CYP17A1 (0.51) | — | |
| SCHEMBL24088159 | 0.64 | L3MBTL1 (0.50) | MAPT | |
| SCHEMBL3195898 | 0.63 | GHSR (0.49) | FAAH | |
| SCHEMBL19067925 | 0.63 | — | — | |
| SCHEMBL697215 | 0.63 | BTK (0.38) | MAPTSMN1; SMN2 | |
| SCHEMBL17312839 | 0.63 | GSK3B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |