Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 10/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527231 | 0.73 | KIF11 (0.36) | — | |
| SCHEMBL4537870 | 0.69 | GAA (0.35) | GAA | |
| SCHEMBL27561236 | 0.68 | PTGS2 (0.42) | — | |
| SCHEMBL27414979 | 0.67 | GAA (0.32) | GAA | |
| SCHEMBL27537707 | 0.67 | GAA (0.32) | GAA | |
| SCHEMBL27746556 | 0.65 | GPR88 (0.35) | GPR88 | |
| SCHEMBL29360497 | 0.64 | ALDH1A1 (0.50) | GAA | |
| SCHEMBL9528642 | 0.64 | RIPK1 (0.65) | MTNR1AMTNR1B | |
| SCHEMBL28802500 | 0.63 | CTSK (0.36) | GPR88GAA | |
| SCHEMBL17574069 | 0.63 | GAA (0.48) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1098849-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-01-15 | — | — | CN | disclosed |
| CN-1227225-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-09-01 | — | — | CN | disclosed |