SCHEMBL2747575

SCHEMBL2747575

C#Cc1c(C(=O)O)cccc1C(F)(c1cccc(C(=O)O)c1C#C)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 3/20 0.38
FABP4 P15090 1/20 0.37
TSHR P16473 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 3/20 0.35
ALB P02768 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
DHODH Q02127 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747181 0.82 HNF4A (0.40) TAS2R14FABP4ADRA2BADRA2CALDH1A1
SCHEMBL1372606 0.80 ALDH1A1 (0.48) TAS2R14FABP4TSHRALDH1A1ALOX15
SCHEMBL3423138 0.79 TAS2R14 (0.40) TAS2R14FABP4TSHRALDH1A1ALOX15
SCHEMBL7150816 0.79 ALB (0.50) TAS2R14FABP4TSHRALDH1A1ALOX15
SCHEMBL5667768 0.78 FABP4 (0.40) TAS2R14FABP4ADRA2BADRA2CALDH1A1
SCHEMBL1712400 0.77 ALDH1A1 (0.52) TSHRALDH1A1ALOX15ALBNAPRT
Benzene SCHEMBL5669425 0.77 ALOX15 (0.43) TAS2R14TSHRALDH1A1ALOX15ALB
SCHEMBL5668183 0.77 ALOX15 (0.43) TAS2R14TSHRALDH1A1ALOX15ALB
Hydrochloric Acid SCHEMBL6349434 0.75 ALDH1A1 (0.50) TSHRALDH1A1ALOX15ALBNAPRT
SCHEMBL5025935 0.74 NPC1 (0.41) TAS2R14FABP4ADRA2BADRA2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed