Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.36 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493350 | 0.93 | RORC (0.41) | THRBRORCGUSBALDH1A1MAPT | |
| SCHEMBL27495704 | 0.89 | TDO2 (0.44) | RORCGUSBALDH1A1MAPTNR3C1 | |
| SCHEMBL27509165 | 0.83 | MPO (0.41) | ALDH1A1MAPTIDO1TDO2 | |
| SCHEMBL27557415 | 0.81 | GAA (0.40) | GUSBALDH1A1MAPT | |
| SCHEMBL27495318 | 0.77 | GUSB (0.39) | GUSBALDH1A1MAPTNR3C1PGR | |
| SCHEMBL27494109 | 0.75 | DRD2 (0.36) | GUSBALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL27495316 | 0.74 | TDO2 (0.42) | ALDH1A1MAPTTDO2 | |
| SCHEMBL27494914 | 0.74 | MMP1 (0.40) | GUSBALDH1A1MAPT | |
| SCHEMBL27510617 | 0.71 | HASPIN (0.46) | RORCALDH1A1MAPTHTT | |
| SCHEMBL27524772 | 0.70 | GPR84 (0.42) | NR3C1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |