Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510617 | 0.81 | HASPIN (0.46) | SMN1; SMN2GAARAB9AKMT2ALMNA | |
| SCHEMBL27511351 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2GAARAB9AKMT2AMEN1 | |
| SCHEMBL27495319 | 0.73 | KDM4E (0.42) | RAB9AKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL27495704 | 0.70 | TDO2 (0.44) | SMN1; SMN2KMT2ALMNAMEN1MAPT | |
| SCHEMBL27509165 | 0.70 | MPO (0.41) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL2203728 | 0.70 | FFAR1 (0.57) | SMN1; SMN2GAARAB9AKMT2AMEN1 | |
| SCHEMBL10399096 | 0.69 | MMP9 (0.52) | KMT2AMEN1CYP1A2CYP2D6HIF1A | |
| SCHEMBL17451237 | 0.69 | UGT2B7 (0.50) | SMN1; SMN2GAARAB9AKMT2AMEN1 | |
| SCHEMBL14349718 | 0.69 | KDM4E (0.51) | KMT2AMEN1NPSR1KDM4EPOLB | |
| SCHEMBL6172465 | 0.69 | TNF (0.56) | SMN1; SMN2GAARAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |